arhgap10 Rho GTPase activating protein 10 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: arhgap10provided by ZNC
Official Full Name: Rho GTPase activating protein 10provided by ZNC
Primary source: ZFIN:ZDB-GENE-060512-221
See related: Ensembl:ENSDARG00000078326 AllianceGenome:ZFIN:ZDB-GENE-060512-221
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: fj86f05; wu:fj86f05; zgc:136983
Summary: Predicted to enable GTPase activator activity. Predicted to act upstream of or within signal transduction. Predicted to be located in cytoplasm. Orthologous to human ARHGAP10 (Rho GTPase activating protein 10). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 1

Exon count:: 23

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	1	NC_007112.7 (36772076..36912619)
105	previous assembly	GRCz10 (GCF_000002035.5)	1	NC_007112.6 (36040049..36180662)

Chromosome 1 - NC_007112.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables GTPase activator activity	IBA Inferred from Biological aspect of Ancestor more info
enables GTPase activator activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within signal transduction	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: rho GTPase-activating protein 10

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001045250.1 → NP_001038715.1 rho GTPase-activating protein 10

See identical proteins and their annotated locations for NP_001038715.1

Status: PROVISIONAL

Source sequence(s)

BC116621

UniProtKB/TrEMBL

A0A8M1NA90, Q1JPR9

Related

ENSDARP00000100587.2, ENSDART00000109314.5

Conserved Domains (5) summary

cd07635
Location:19 → 225

BAR_GRAF2; The Bin/Amphiphysin/Rvs (BAR) domain of GTPase Regulator Associated with Focal adhesion 2

cd01249
Location:267 → 373

BAR-PH_GRAF_family; GTPase Regulator Associated with Focal adhesion and related proteins Pleckstrin homology (PH) domain

pfam00169
Location:269 → 367

PH; PH domain

cl02570
Location:367 → 566

RhoGAP; RhoGAP: GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when ...

cl17036
Location:710 → 763

SH3; Src Homology 3 domain superfamily