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    rab5if RAB5 interacting factor [ Danio rerio (zebrafish) ]

    Gene ID: 334006, updated on 9-Dec-2024

    Summary

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    Official Symbol
    rab5ifprovided by ZNC
    Official Full Name
    RAB5 interacting factorprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030131-5938
    See related
    Ensembl:ENSDARG00000074790 AllianceGenome:ZFIN:ZDB-GENE-030131-5938
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    fi26d09; c20orf24; zgc:55393; wu:fi26d09; c23h20orf24
    Summary
    Predicted to act upstream of or within mitochondrial respirasome assembly. Predicted to be located in endoplasmic reticulum membrane. Human ortholog(s) of this gene implicated in craniofacial dysmorphism, skeletal anomalies, and impaired intellectual development syndrome 2. Orthologous to human RAB5IF (RAB5 interacting factor). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See rab5if in Genome Data Viewer
    Location:
    chromosome: 23
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 23 NC_007134.7 (2906129..2913201)
    105 previous assembly GRCz10 (GCF_000002035.5) 23 NC_007134.6 (2962520..2969592)

    Chromosome 23 - NC_007134.7Genomic Context describing neighboring genes Neighboring gene phospholipase C, gamma 1 Neighboring gene zinc fingers and homeoboxes 3b Neighboring gene DEAH-box helicase 35 Neighboring gene uncharacterized LOC137489067

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Analyses of the extent of shared synteny and conserved gene orders between the genome of Fugu rubripes and human 20q. Smith SF, et al. Genome Res, 2002 May. PMID 11997344, Free PMC Article
    2. Xmrk, kras and myc transgenic zebrafish liver cancer models share molecular signatures with subsets of human hepatocellular carcinoma. Zheng W, et al. PLoS One, 2014. PMID 24633177, Free PMC Article
    3. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    5. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Process Evidence Code Pubs
    acts_upstream_of_or_within mitochondrial respirasome assembly IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in endoplasmic reticulum membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    GEL complex subunit OPTI
    Names
    c23h20orf24 homolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_199850.2 → NP_956144.2  GEL complex subunit OPTI

      Status: VALIDATED

      Source sequence(s)
      AW777652, CT613988, EH540625
      UniProtKB/TrEMBL
      A0A8M1PC00, F1RD59
      Related
      ENSDARP00000100542.2, ENSDART00000109304.4
      Conserved Domains (1) summary
      pfam07019
      Location:42 → 118
      Rab5ip; Rab5-interacting protein (Rab5ip)

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007134.7 Reference GRCz11 Primary Assembly

      Range
      2906129..2913201
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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