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    ppp4r2a protein phosphatase 4, regulatory subunit 2a [ Danio rerio (zebrafish) ]

    Gene ID: 326723, updated on 9-Dec-2024

    Summary

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    Official Symbol
    ppp4r2aprovided by ZNC
    Official Full Name
    protein phosphatase 4, regulatory subunit 2aprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030131-4922
    See related
    Ensembl:ENSDARG00000026540 AllianceGenome:ZFIN:ZDB-GENE-030131-4922
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    ppp4r2; fe11b04; wu:fe11b04
    Summary
    Predicted to enable protein phosphatase regulator activity. Predicted to be part of protein phosphatase 4 complex. Predicted to be active in cytoplasm and nucleus. Orthologous to human PPP4R2 (protein phosphatase 4 regulatory subunit 2). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See ppp4r2a in Genome Data Viewer
    Location:
    chromosome: 23
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 23 NC_007134.7 (10805186..10826997)
    105 previous assembly GRCz10 (GCF_000002035.5) 23 NC_007134.6 (10870216..10892027)

    Chromosome 23 - NC_007134.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC101882482 Neighboring gene RING1 and YY1 binding protein a Neighboring gene PDZ domain containing RING finger 3a Neighboring gene contactin 3a, tandem duplicate 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
    4. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables protein phosphatase regulator activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables protein phosphatase regulator activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of protein phosphatase 4 complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of protein phosphatase 4 complex IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    serine/threonine-protein phosphatase 4 regulatory subunit 2-A
    Names
    protein phosphatase 4, regulatory subunit 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001115140.1 → NP_001108612.1  serine/threonine-protein phosphatase 4 regulatory subunit 2-A

      Status: PROVISIONAL

      Source sequence(s)
      CT027567
      UniProtKB/Swiss-Prot
      A7MBR6, Q6P964
      UniProtKB/TrEMBL
      A0A8M1NGM0, F1QCN7
      Related
      ENSDARP00000036492.6, ENSDART00000035693.7
      Conserved Domains (1) summary
      pfam09184
      Location:6 → 250
      PPP4R2; PPP4R2

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007134.7 Reference GRCz11 Primary Assembly

      Range
      10805186..10826997
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q6P964.2 GenPept UniProtKB/Swiss-Prot:Q6P964

    Gene LinkOut

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