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    poll polymerase (DNA directed), lambda [ Danio rerio (zebrafish) ]

    Gene ID: 406697, updated on 9-Dec-2024

    Summary

    Official Symbol
    pollprovided by ZNC
    Official Full Name
    polymerase (DNA directed), lambdaprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040426-2712
    See related
    Ensembl:ENSDARG00000039613 AllianceGenome:ZFIN:ZDB-GENE-040426-2712
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:66320; zgc:77901; wu:fe49a04
    Summary
    Predicted to enable DNA-directed DNA polymerase activity. Predicted to be involved in double-strand break repair via nonhomologous end joining. Predicted to act upstream of or within DNA biosynthetic process and DNA repair. Predicted to be active in nucleus. Is expressed in head. Orthologous to human POLL (DNA polymerase lambda). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    NEW
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    Genomic context

    See poll in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 1 NC_007112.7 (31657880..31672343)
    105 previous assembly GRCz10 (GCF_000002035.5) 1 NC_007112.6 (30925312..30939775)

    Chromosome 1 - NC_007112.7Genomic Context describing neighboring genes Neighboring gene fibroblast growth factor 8b Neighboring gene deleted in primary ciliary dyskinesia homolog (mouse) Neighboring gene WW domain binding protein 1-like b Neighboring gene arsenite methyltransferase

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Markers

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables DNA polymerase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables DNA-directed DNA polymerase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables DNA-directed DNA polymerase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables nucleotidyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables transferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within DNA biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within DNA damage response IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within DNA repair IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in double-strand break repair via nonhomologous end joining IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    DNA polymerase lambda
    NP_998408.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_213243.1NP_998408.1  DNA polymerase lambda

      See identical proteins and their annotated locations for NP_998408.1

      Status: PROVISIONAL

      Source sequence(s)
      BC065469
      UniProtKB/TrEMBL
      Q6P0S1
      Related
      ENSDARP00000057879.4, ENSDART00000057880.5
      Conserved Domains (3) summary
      cd00141
      Location:246564
      NT_POLXc; Nucleotidyltransferase (NT) domain of family X DNA Polymerases
      smart00483
      Location:243565
      POLXc; DNA polymerase X family
      cd00027
      Location:46122
      BRCT; Breast Cancer Suppressor Protein (BRCA1), carboxy-terminal domain. The BRCT domain is found within many DNA damage repair and cell cycle checkpoint proteins. The unique diversity of this domain superfamily allows BRCT modules to interact forming homo ...

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007112.7 Reference GRCz11 Primary Assembly

      Range
      31657880..31672343
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)