gpm6ab glycoprotein M6Ab [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: gpm6abprovided by ZNC
Official Full Name: glycoprotein M6Abprovided by ZNC
Primary source: ZFIN:ZDB-GENE-030710-8
See related: Ensembl:ENSDARG00000004621 AllianceGenome:ZFIN:ZDB-GENE-030710-8
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: gm6a; DMbeta2
Summary: Acts upstream of or within neuron projection development and regulation of filopodium assembly. Predicted to be located in dendritic spine and membrane. Predicted to be active in several cellular components, including axonal growth cone; filopodium; and neuronal cell body. Is expressed in nervous system; optic vesicle; and trigeminal placode. Orthologous to human GPM6A (glycoprotein M6A). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 1

Exon count:: 9

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	1	NC_007112.7 (38649141..38756908, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	1	NC_007112.6 (37930837..38038630, complement)

Chromosome 1 - NC_007112.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

the phosphorylation status of zebrafish M6Ab at serine 263 is critical for its role in regulating filopodium formation and neurite outgrowth
Title: Phosphorylation of the zebrafish M6Ab at serine 263 contributes to filopodium formation in PC12 cells and neurite outgrowth in zebrafish embryos.

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General gene information

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Gene Ontology Provided by ZFIN

Process	Evidence Code	Pubs
involved_in neuron projection development	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within neuron projection development	IDA Inferred from Direct Assay more info	PubMed
acts_upstream_of_or_within regulation of filopodium assembly	IDA Inferred from Direct Assay more info	PubMed

Component	Evidence Code	Pubs
is_active_in axonal growth cone	IBA Inferred from Biological aspect of Ancestor more info
located_in dendritic spine	IEA Inferred from Electronic Annotation more info
is_active_in filopodium	IBA Inferred from Biological aspect of Ancestor more info
located_in membrane	IEA Inferred from Electronic Annotation more info
is_active_in neuronal cell body	IBA Inferred from Biological aspect of Ancestor more info
is_active_in plasma membrane	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: glycoprotein M6Ab

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.