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    mul3 mitochondrial E3 ubiquitin protein ligase 3 [ Danio rerio (zebrafish) ]

    Gene ID: 402879, updated on 9-Dec-2024

    Summary

    Official Symbol
    mul3provided by ZNC
    Official Full Name
    mitochondrial E3 ubiquitin protein ligase 3provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-240328-1
    See related
    Ensembl:ENSDARG00000114019 AllianceGenome:ZFIN:ZDB-GENE-240328-1
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Summary
    Predicted to enable ligase activity; metal ion binding activity; and ubiquitin-protein transferase activity. Predicted to act upstream of or within protein ubiquitination. Predicted to be located in mitochondrial outer membrane. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See mul3 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 2 NC_007113.7 (2620617..2624945, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 2 NC_007113.6 (2778719..2783376, complement)

    Chromosome 2 - NC_007113.7Genomic Context describing neighboring genes Neighboring gene corticotropin-releasing factor receptor 2 Neighboring gene myosin, light chain 13 Neighboring gene translation initiation factor eIF2B subunit epsilon-like Neighboring gene SERPINE1 mRNA binding protein 1b Neighboring gene aquaporin 1a (Colton blood group), tandem duplicate 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Markers

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables ligase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables transferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables ubiquitin-protein transferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within organelle organization IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within protein ubiquitination IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in mitochondrial outer membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    mitochondrial ubiquitin ligase activator of nfkb 1-A

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007113.7 Reference GRCz11 Primary Assembly

      Range
      2620617..2624945 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005171126.5XP_005171183.1  mitochondrial ubiquitin ligase activator of nfkb 1-A

      See identical proteins and their annotated locations for XP_005171183.1

      UniProtKB/TrEMBL
      A0A2R8Q6C7, A0A8M2BIE5
      Related
      ENSDARP00000146630.1, ENSDART00000190568.1
      Conserved Domains (1) summary
      pfam12483
      Location:96222
      GIDE; E3 Ubiquitin ligase
    2. XM_005171125.5XP_005171182.1  mitochondrial ubiquitin ligase activator of nfkb 1-A

      See identical proteins and their annotated locations for XP_005171182.1

      UniProtKB/TrEMBL
      A0A2R8Q6C7, A0A8M2BIE5
      Conserved Domains (1) summary
      pfam12483
      Location:96222
      GIDE; E3 Ubiquitin ligase
    3. XM_005171127.5XP_005171184.1  mitochondrial ubiquitin ligase activator of nfkb 1-A

      See identical proteins and their annotated locations for XP_005171184.1

      UniProtKB/TrEMBL
      A0A2R8Q6C7, A0A8M2BIE5
      Conserved Domains (1) summary
      pfam12483
      Location:96222
      GIDE; E3 Ubiquitin ligase