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    spcs3 signal peptidase complex subunit 3 [ Danio rerio (zebrafish) ]

    Gene ID: 405884, updated on 9-Dec-2024

    Summary

    Official Symbol
    spcs3provided by ZNC
    Official Full Name
    signal peptidase complex subunit 3provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040426-2206
    See related
    Ensembl:ENSDARG00000089976 AllianceGenome:ZFIN:ZDB-GENE-040426-2206
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:85675
    Summary
    Predicted to be involved in protein targeting to ER and signal peptide processing. Predicted to be located in endoplasmic reticulum and membrane. Predicted to be part of signal peptidase complex. Orthologous to human SPCS3 (signal peptidase complex subunit 3). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See spcs3 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 1 NC_007112.7 (38818316..38822163)
    105 previous assembly GRCz10 (GCF_000002035.5) 1 NC_007112.6 (38100012..38103859)

    Chromosome 1 - NC_007112.7Genomic Context describing neighboring genes Neighboring gene WD repeat domain 17 Neighboring gene ankyrin repeat and SOCS box containing 5b Neighboring gene vascular endothelial growth factor c Neighboring gene teneurin transmembrane protein 3 Neighboring gene microRNA mir-2197

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Markers

    Clone Names

    • MGC85675

    Gene Ontology Provided by ZFIN

    Process Evidence Code Pubs
    involved_in protein targeting to ER IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in signal peptide processing IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within signal peptide processing IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    part_of signal peptidase complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of signal peptidase complex IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    signal peptidase complex subunit 3
    Names
    signal peptidase complex subunit 3 homolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_212948.1NP_998113.1  signal peptidase complex subunit 3

      See identical proteins and their annotated locations for NP_998113.1

      Status: PROVISIONAL

      Source sequence(s)
      BC067570
      UniProtKB/TrEMBL
      A0A8M1PEA7, Q6NWJ2
      Related
      ENSDARP00000139098.1, ENSDART00000166864.2
      Conserved Domains (1) summary
      pfam04573
      Location:4173
      SPC22; Signal peptidase subunit

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007112.7 Reference GRCz11 Primary Assembly

      Range
      38818316..38822163
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)