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    serbp1b SERPINE1 mRNA binding protein 1b [ Danio rerio (zebrafish) ]

    Gene ID: 797732, updated on 9-Dec-2024

    Summary

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    Official Symbol
    serbp1bprovided by ZNC
    Official Full Name
    SERPINE1 mRNA binding protein 1bprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-031118-196
    See related
    Ensembl:ENSDARG00000087421 AllianceGenome:ZFIN:ZDB-GENE-031118-196
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    fc66f06; wu:fc66f06
    Summary
    Predicted to enable mRNA 3'-UTR binding activity. Predicted to act upstream of or within regulation of translation. Predicted to be active in cytoplasm and nucleus. Orthologous to human SERBP1 (SERPINE1 mRNA binding protein 1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See serbp1b in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 2 NC_007113.7 (2628405..2642077, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 2 NC_007113.6 (2786506..2800211, complement)

    Chromosome 2 - NC_007113.7Genomic Context describing neighboring genes Neighboring gene myosin, light chain 13 Neighboring gene translation initiation factor eIF2B subunit epsilon-like Neighboring gene mitochondrial E3 ubiquitin protein ligase 3 Neighboring gene aquaporin 1a (Colton blood group), tandem duplicate 1 Neighboring gene aquaporin 1a (Colton blood group), tandem duplicate 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
    3. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables mRNA 3'-UTR binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within regulation of translation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    SERPINE1 mRNA-binding protein 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007113.7 Reference GRCz11 Primary Assembly

      Range
      2628405..2642077 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_001338162.9 → XP_001338198.4  SERPINE1 mRNA-binding protein 1 isoform X2

      UniProtKB/TrEMBL
      A0A8M1Q7B8
      Conserved Domains (2) summary
      pfam04774
      Location:181 → 283
      HABP4_PAI-RBP1; Hyaluronan / mRNA binding family
      pfam16174
      Location:5 → 97
      IHABP4_N; Intracellular hyaluronan-binding protein 4 N-terminal

    2. XM_005171128.4 → XP_005171185.1  SERPINE1 mRNA-binding protein 1 isoform X1

      UniProtKB/TrEMBL
      A0A8M2BIU7, E7EYQ0
      Related
      ENSDARP00000109449.3, ENSDART00000124032.4
      Conserved Domains (2) summary
      pfam04774
      Location:181 → 283
      HABP4_PAI-RBP1; Hyaluronan / mRNA binding family
      pfam16174
      Location:5 → 97
      IHABP4_N; Intracellular hyaluronan-binding protein 4 N-terminal
    Nucleotide Protein Strain
    Heading Accession and Version

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