metrnla meteorin like, glial cell differentiation regulator a [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: metrnlaprovided by ZNC
Official Full Name: meteorin like, glial cell differentiation regulator aprovided by ZNC
Primary source: ZFIN:ZDB-GENE-040426-1917
See related: Ensembl:ENSDARG00000101914 AllianceGenome:ZFIN:ZDB-GENE-040426-1917
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: metrnl; fc90a08; fj23b04; zgc:56225; wu:fc90a08; wu:fj23b04
Summary: Predicted to enable hormone activity. Predicted to be involved in several processes, including brown fat cell differentiation; positive regulation of brown fat cell differentiation; and response to muscle activity. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Is expressed in several structures, including axis; central nervous system; otic placode; pronephric duct; and segmental plate. Orthologous to human METRNL (meteorin like, glial cell differentiation regulator). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 3

Exon count:: 4

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	3	NC_007114.7 (48473530..48489656)
105	previous assembly	GRCz10 (GCF_000002035.5)	3	NC_007114.6 (44328119..44344245)

Chromosome 3 - NC_007114.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

fj23b04.y1 (e-PCR)
- UniSTS:198811

fc90a08.x1 (e-PCR)
- UniSTS:188377

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables hormone activity	IBA Inferred from Biological aspect of Ancestor more info
enables hormone activity	IEA Inferred from Electronic Annotation more info
enables hormone activity	ISS Inferred from Sequence or Structural Similarity more info

Process	Evidence Code	Pubs
involved_in brown fat cell differentiation	ISS Inferred from Sequence or Structural Similarity more info
involved_in energy homeostasis	IBA Inferred from Biological aspect of Ancestor more info
involved_in energy homeostasis	ISS Inferred from Sequence or Structural Similarity more info
involved_in negative regulation of inflammatory response	ISS Inferred from Sequence or Structural Similarity more info
involved_in positive regulation of brown fat cell differentiation	IBA Inferred from Biological aspect of Ancestor more info
involved_in positive regulation of brown fat cell differentiation	ISS Inferred from Sequence or Structural Similarity more info
involved_in response to cold	ISS Inferred from Sequence or Structural Similarity more info
involved_in response to muscle activity	ISS Inferred from Sequence or Structural Similarity more info

Component	Evidence Code	Pubs
located_in extracellular region	IEA Inferred from Electronic Annotation more info
is_active_in extracellular space	IBA Inferred from Biological aspect of Ancestor more info
located_in extracellular space	ISS Inferred from Sequence or Structural Similarity more info

General protein information

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Preferred Names: meteorin-like protein

Names: meteorin, glial cell differentiation regulator-like a

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.