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    serhl serine hydrolase like [ Danio rerio (zebrafish) ]

    Gene ID: 322648, updated on 4-Jan-2025

    Summary

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    Official Symbol
    serhlprovided by ZNC
    Official Full Name
    serine hydrolase likeprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030131-1368
    See related
    Ensembl:ENSDARG00000032340 AllianceGenome:ZFIN:ZDB-GENE-030131-1368
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:55804; wu:fb69a04
    Summary
    Predicted to enable hydrolase activity. Orthologous to several human genes including SERHL (serine hydrolase like (pseudogene)). [provided by Alliance of Genome Resources, Jan 2025]
    Orthologs
    human mouse all
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    Genomic context

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    See serhl in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 1 NC_007112.7 (45650283..45662774, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 1 NC_007112.6 (44958489..44970979, complement)

    Chromosome 1 - NC_007112.7Genomic Context describing neighboring genes Neighboring gene septin 3 Neighboring gene small integral membrane protein 45 Neighboring gene trafficking protein particle complex subunit 5 Neighboring gene mucolipin TRP cation channel 1a

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Dysregulation of Microglial Function Contributes to Neuronal Impairment in Mcoln1a-Deficient Zebrafish. Jin W, et al. iScience, 2019 Mar 29. PMID 30897512, Free PMC Article
    2. Insights Into the Peroxisomal Protein Inventory of Zebrafish. Kamoshita M, et al. Front Physiol, 2022. PMID 35295584, Free PMC Article
    3. Hematopoietic gene expression profile in zebrafish kidney marrow. Song HD, et al. Proc Natl Acad Sci U S A, 2004 Nov 16. PMID 15520368, Free PMC Article
    4. The zebrafish gene map defines ancestral vertebrate chromosomes. Woods IG, et al. Genome Res, 2005 Sep. PMID 16109975, Free PMC Article
    5. 15000 unique zebrafish EST clusters and their future use in microarray for profiling gene expression patterns during embryogenesis. Lo J, et al. Genome Res, 2003 Mar. PMID 12618376, Free PMC Article

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables hydrolase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables hydrolase activity, acting on ester bonds IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    serine hydrolase-like protein
    Names
    kraken-like

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_199615.2 → NP_955909.2  serine hydrolase-like protein

      Status: VALIDATED

      Source sequence(s)
      BX511120, EH457337, EH483060
      UniProtKB/Swiss-Prot
      A2BGU9, Q6NYD3, Q803G4
      Related
      ENSDARP00000042157.3, ENSDART00000042158.5
      Conserved Domains (2) summary
      COG0596
      Location:35 → 308
      MhpC; Pimeloyl-ACP methyl ester carboxylesterase [Coenzyme transport and metabolism, General function prediction only]
      pfam12695
      Location:44 → 144
      Abhydrolase_5; Alpha/beta hydrolase family

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007112.7 Reference GRCz11 Primary Assembly

      Range
      45650283..45662774 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_068223271.1 → XP_068079372.1  serine hydrolase-like protein isoform X1

    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A2BGU9.1 GenPept UniProtKB/Swiss-Prot:A2BGU9

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