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    spc24 SPC24 component of NDC80 kinetochore complex [ Danio rerio (zebrafish) ]

    Gene ID: 554147, updated on 9-Dec-2024

    Summary

    Official Symbol
    spc24provided by ZNC
    Official Full Name
    SPC24 component of NDC80 kinetochore complexprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-050522-456
    See related
    Ensembl:ENSDARG00000093622 AllianceGenome:ZFIN:ZDB-GENE-050522-456
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    wu:fb79a02; zgc:110417
    Summary
    Predicted to contribute to microtubule binding activity. Predicted to be involved in chromosome segregation. Predicted to act upstream of or within cell division. Predicted to be located in kinetochore and nucleus. Predicted to be part of Ndc80 complex. Orthologous to human SPC24 (SPC24 component of NDC80 kinetochore complex). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See spc24 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 3 NC_007114.7 (19355915..19363977)
    105 previous assembly GRCz10 (GCF_000002035.5) 3 NC_007114.6 (19206175..19214237)

    Chromosome 3 - NC_007114.7Genomic Context describing neighboring genes Neighboring gene low density lipoprotein receptor a Neighboring gene Z30 small nucleolar RNA Neighboring gene KRI1 homolog Neighboring gene sphingosine-1-phosphate receptor 5a Neighboring gene zgc:123297

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Markers

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    contributes_to microtubule binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within cell division IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in chromosome segregation IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    part_of Ndc80 complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of Ndc80 complex ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in chromosome IEA
    Inferred from Electronic Annotation
    more info
     
    located_in chromosome, centromeric region IEA
    Inferred from Electronic Annotation
    more info
     
    located_in kinetochore IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    kinetochore protein Spc24
    Names
    SPC24, NDC80 kinetochore complex component, homolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001024440.1NP_001019611.1  kinetochore protein Spc24

      See identical proteins and their annotated locations for NP_001019611.1

      Status: PROVISIONAL

      Source sequence(s)
      BC095251
      UniProtKB/Swiss-Prot
      Q503N2, Q6DG65
      UniProtKB/TrEMBL
      B2GQP4
      Related
      ENSDARP00000059307.6, ENSDART00000059308.7
      Conserved Domains (1) summary
      pfam08286
      Location:88197
      Spc24; Spc24 subunit of Ndc80

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007114.7 Reference GRCz11 Primary Assembly

      Range
      19355915..19363977
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)