foxg1a forkhead box G1a [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: foxg1aprovided by ZNC
Official Full Name: forkhead box G1aprovided by ZNC
Primary source: ZFIN:ZDB-GENE-990415-267
See related: Ensembl:ENSDARG00000070769 AllianceGenome:ZFIN:ZDB-GENE-990415-267
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: bf1; BF-1; foxg1; zgc:109850
Summary: Predicted to enable sequence-specific double-stranded DNA binding activity. Acts upstream of or within embryonic retina morphogenesis in camera-type eye; neuron differentiation; and nose development. Predicted to be active in nucleus. Is expressed in several structures, including anterior neural keel; immature eye; nervous system; neuroectoderm; and presumptive telencephalon. Orthologous to human FOXG1 (forkhead box G1). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 17

Exon count:: 2

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	17	NC_007128.7 (29104743..29119362, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	17	NC_007128.6 (29088483..29102500, complement)

Chromosome 17 - NC_007128.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Evolutionarily conserved roles of foxg1a in the developing subpallium of zebrafish embryos.
Title: Evolutionarily conserved roles of foxg1a in the developing subpallium of zebrafish embryos.
Results suggest that foxg1b and foxg1c have undergone expression pattern divergence during evolution that has resulted in functional specialization.
Title: Distinct expression of two foxg1 paralogues in zebrafish.
These findings identify a key direct target of Foxg1, and uncover a simple molecular mechanism by which Foxg1 integrates two opposing signaling centers.
Title: Integration of telencephalic Wnt and hedgehog signaling center activities by Foxg1.

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General gene information

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Markers

Z21435 (e-PCR)
- UniSTS:204704

fj15d01.y1 (e-PCR)
- UniSTS:198612

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables DNA binding	IEA Inferred from Electronic Annotation more info
enables DNA-binding transcription factor activity	IEA Inferred from Electronic Annotation more info
enables sequence-specific DNA binding	IEA Inferred from Electronic Annotation more info
enables sequence-specific double-stranded DNA binding	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within embryonic retina morphogenesis in camera-type eye	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within neuron differentiation	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within nose development	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within regulation of DNA-templated transcription	IEA Inferred from Electronic Annotation more info
involved_in regulation of transcription by RNA polymerase II	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info
located_in nucleus	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: forkhead box protein G1

Names: brain factor 1; forkhead box G1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.