cox8a cytochrome c oxidase subunit 8A [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: cox8aprovided by ZNC
Official Full Name: cytochrome c oxidase subunit 8Aprovided by ZNC
Primary source: ZFIN:ZDB-GENE-030131-9136
See related: Ensembl:ENSDARG00000095273 AllianceGenome:ZFIN:ZDB-GENE-030131-9136
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: fb01d11; coxXVIII; zehn2228; wu:fb01d11; hm:zehn2228
Summary: Predicted to act upstream of or within mitochondrial electron transport, cytochrome c to oxygen. Predicted to be located in mitochondrial inner membrane. Predicted to be part of respiratory chain complex IV. Predicted to be active in mitochondrion. Is expressed in brain; gill; heart; liver; and skeletal muscle. Human ortholog(s) of this gene implicated in mitochondrial complex IV deficiency nuclear type 15. Orthologous to human COX8A (cytochrome c oxidase subunit 8A). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 21

Exon count:: 2

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	21	NC_007132.7 (28496193..28500703)
105	previous assembly	GRCz10 (GCF_000002035.5)	21	NC_007132.6 (28459498..28464008)

Chromosome 21 - NC_007132.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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Markers

AI617873 (e-PCR)
- UniSTS:206160

fb01d11.x1 (e-PCR)
- UniSTS:202652

Gene Ontology Provided by ZFIN

Process	Evidence Code	Pubs
acts_upstream_of_or_within mitochondrial electron transport, cytochrome c to oxygen	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in membrane	IEA Inferred from Electronic Annotation more info
located_in mitochondrial inner membrane	IEA Inferred from Electronic Annotation more info
is_active_in mitochondrion	IBA Inferred from Biological aspect of Ancestor more info
part_of respiratory chain complex IV	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: cytochrome c oxidase subunit 8A, mitochondrial

Names: cytochrome c oxidase subunit VIIIA (ubiquitous)

NP_001289982.1

EC 7.1.1.9

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001303053.1 → NP_001289982.1 cytochrome c oxidase subunit 8A, mitochondrial

Status: VALIDATED

Source sequence(s)

CR749775, EH442681, EH443530

UniProtKB/TrEMBL

A0A8M1P768, E9QFA6

Related

ENSDARP00000119314.1, ENSDART00000138236.2

Conserved Domains (1) summary

pfam02285
Location:29 → 69

COX8; Cytochrome oxidase c subunit VIII