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    cyc1 cytochrome c-1 [ Danio rerio (zebrafish) ]

    Gene ID: 564379, updated on 9-Dec-2024

    Summary

    Official Symbol
    cyc1provided by ZNC
    Official Full Name
    cytochrome c-1provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-031105-2
    See related
    Ensembl:ENSDARG00000038075 AllianceGenome:ZFIN:ZDB-GENE-031105-2
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    fb80h03; sr:nyz104; im:6911272; wu:fb80h03; zgc:123089
    Summary
    Predicted to enable heme binding activity; metal ion binding activity; and ubiquinol-cytochrome-c reductase activity. Predicted to be involved in mitochondrial electron transport, ubiquinol to cytochrome c. Predicted to be located in mitochondrial inner membrane. Predicted to be part of respiratory chain complex III. Is expressed in several structures, including adaxial cell; digestive system; eye; midbrain; and musculature system. Human ortholog(s) of this gene implicated in mitochondrial complex III deficiency nuclear type 6. Orthologous to human CYC1 (cytochrome c1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See cyc1 in Genome Data Viewer
    Location:
    chromosome: 6
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 6 NC_007117.7 (50381572..50390093)
    105 previous assembly GRCz10 (GCF_000002035.5) 6 NC_007117.6 (50382353..50390874)

    Chromosome 6 - NC_007117.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC101886784 Neighboring gene uncharacterized LOC137496022 Neighboring gene ERGIC and golgi 3 Neighboring gene reactive oxygen species modulator 1 Neighboring gene myelocytomatosis oncogene homolog

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Markers

    Clone Names

    • MGC123089

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables electron transfer activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables heme binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables ubiquinol-cytochrome-c reductase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in mitochondrial electron transport, ubiquinol to cytochrome c IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in mitochondrial inner membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
     
    part_of respiratory chain complex III IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    cytochrome c1, heme protein, mitochondrial
    NP_001032470.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001037393.2NP_001032470.1  cytochrome c1, heme protein, mitochondrial

      See identical proteins and their annotated locations for NP_001032470.1

      Status: VALIDATED

      Source sequence(s)
      BX649289, EH434095, EH477592, EH598125
      UniProtKB/TrEMBL
      A4FVJ3, Q3B7R0
      Related
      ENSDARP00000055503.4, ENSDART00000055504.6
      Conserved Domains (2) summary
      COG2857
      Location:66297
      CYT1; Cytochrome c1 [Energy production and conversion]
      pfam02167
      Location:78296
      Cytochrom_C1; Cytochrome C1 family

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007117.7 Reference GRCz11 Primary Assembly

      Range
      50381572..50390093
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)