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    or70a4 odorant receptor, family 70, subfamily A, member 4 [ Danio rerio (zebrafish) ]

    Gene ID: 80361, updated on 9-Dec-2024

    Summary

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    Official Symbol
    or70a4provided by ZNC
    Official Full Name
    odorant receptor, family 70, subfamily A, member 4provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-010309-3
    See related
    Ensembl:ENSDARG00000035048 AllianceGenome:ZFIN:ZDB-GENE-010309-3
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    or9.3; or21.41; or115-10; zgc:123156
    Summary
    Predicted to enable odorant binding activity and olfactory receptor activity. Predicted to be involved in detection of chemical stimulus involved in sensory perception of smell. Predicted to act upstream of or within G protein-coupled receptor signaling pathway. Predicted to be active in membrane. Is expressed in olfactory epithelium. Orthologous to several human genes including OR1A1 (olfactory receptor family 1 subfamily A member 1); OR1A2 (olfactory receptor family 1 subfamily A member 2); and OR1C1 (olfactory receptor family 1 subfamily C member 1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See or70a4 in Genome Data Viewer
    Location:
    chromosome: 21
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 21 NC_007132.7 (40236650..40237591)
    105 previous assembly GRCz10 (GCF_000002035.5) 21 NC_007132.6 (40212346..40214421)

    Chromosome 21 - NC_007132.7Genomic Context describing neighboring genes Neighboring gene odorant receptor, family 70, subfamily A, member 3 Neighboring gene odorant receptor, family 70, subfamily A, member 11 Neighboring gene odorant receptor, family 70, subfamily A, member 13 Neighboring gene olfactory receptor, family 70, subfamily A, member 5

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Identification of 24 genes and two pseudogenes coding for olfactory receptors in Japanese loach, classified into four subfamilies: a putative evolutionary process for fish olfactory receptor genes by comprehensive phylogenetic analysis. Irie-Kushiyama S, et al. Gene, 2004 Jan 21. PMID 14697517
    2. Asynchronous onset of odorant receptor expression in the developing zebrafish olfactory system. Barth AL, et al. Neuron, 1996 Jan. PMID 8562087
    3. Transcriptome Analysis of Zebrafish Olfactory Epithelium Reveal Sexual Differences in Odorant Detection. Wang Y, et al. Genes (Basel), 2020 May 27. PMID 32471067, Free PMC Article
    4. On the origin and evolution of vertebrate olfactory receptor genes: comparative genome analysis among 23 chordate species. Niimura Y. Genome Biol Evol, 2009 Apr 30. PMID 20333175, Free PMC Article
    5. The odorant receptor repertoire of teleost fish. Alioto TS, et al. BMC Genomics, 2005 Dec 6. PMID 16332259, Free PMC Article

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC123156

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables odorant binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables olfactory receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables olfactory receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within G protein-coupled receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in detection of chemical stimulus involved in sensory perception of smell IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    odorant receptor 115-10
    Names
    odorant receptor, family 9, member 3
    odorant receptor, family F, subfamily 115, member 10
    receptor 10

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_131743.1 → NP_571818.1  odorant receptor 115-10

      See identical proteins and their annotated locations for NP_571818.1

      Status: PROVISIONAL

      Source sequence(s)
      U42392
      UniProtKB/TrEMBL
      Q2PRI2, Q90426
      Related
      ENSDARP00000121191.1, ENSDART00000132308.3
      Conserved Domains (2) summary
      pfam00001
      Location:41 → 290
      7tm_1; 7 transmembrane receptor (rhodopsin family)
      cl21561
      Location:34 → 306
      7tm_4; Olfactory receptor

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007132.7 Reference GRCz11 Primary Assembly

      Range
      40236650..40237591
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_001111084.1: Suppressed sequence

      Description
      NM_001111084.1: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript.
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

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