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    TOM1 tobamovirus multiplication 1 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 828267, updated on 18-Sep-2024

    Summary

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    Official Symbol
    TOM1
    Official Full Name
    tobamovirus multiplication 1
    Primary source
    TAIR:AT4G21790
    Locus tag
    AT4G21790
    See related
    Araport:AT4G21790
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ATTOM1; F17L22.250; F17L22_250; tobamovirus multiplication 1
    Summary
    encodes a host factor that is required for TMV virus multiplication.
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    Genomic context

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    See TOM1 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    11
    Sequence:
    Chromosome: 4; NC_003075.7 (11569524..11572595)

    Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene beta-glucosidase 47 Neighboring gene Pseudouridine synthase family protein Neighboring gene uncharacterized protein Neighboring gene P-loop containing nucleoside triphosphate hydrolases superfamily protein Neighboring gene DERLIN-2.1 Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003075.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Effects of the tom1 mutation of Arabidopsis thaliana on the multiplication of tobacco mosaic virus RNA in protoplasts. Ishikawa M, et al. J Virol, 1993 Sep. PMID 8350399, Free PMC Article
    2. Subcellular localization of host and viral proteins associated with tobamovirus RNA replication. Hagiwara Y, et al. EMBO J, 2003 Jan 15. PMID 12514140, Free PMC Article
    3. Arabidopsis TOBAMOVIRUS MULTIPLICATION (TOM) 2 locus encodes a transmembrane protein that interacts with TOM1. Tsujimoto Y, et al. EMBO J, 2003 Jan 15. PMID 12514139, Free PMC Article
    4. A proteomics dissection of Arabidopsis thaliana vacuoles isolated from cell culture. Jaquinod M, et al. Mol Cell Proteomics, 2007 Mar. PMID 17151019, Free PMC Article
    5. Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana. Mayer K, et al. Nature, 1999 Dec 16. PMID 10617198

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_118299.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within viral replication complex formation and maintenance IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in plant-type vacuole HDA PubMed 
    located_in plant-type vacuole membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in vacuolar membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    tobamovirus multiplication 1
    NP_567636.1
    • tobamovirus multiplication 1 (TOM1); INVOLVED IN: viral replication complex formation and maintenance; LOCATED IN: vacuolar membrane, plasma membrane; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Protein of unknown function DUF1084 (InterPro:IPR009457); BEST Arabidopsis thaliana protein match is: tobamovirus multiplication protein 3 (TAIR:AT2G02180.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003075.7 Reference assembly

      Range
      11569524..11572595
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_118299.4 → NP_567636.1  tobamovirus multiplication 1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_567636.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9FEG2, Q9SVR8
      UniProtKB/TrEMBL
      A0A178UT97, A0A5S9XV82
      Conserved Domains (1) summary
      pfam06454
      Location:19 → 289
      DUF1084; Protein of unknown function (DUF1084)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9FEG2.1

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