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    CG10340 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 42020, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG10340provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0022344
    Locus tag
    Dmel_CG10340
    See related
    AllianceGenome:FB:FBgn0022344
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    anon-EST:fe2A5; anon2A5; Dmel\CG10340
    Summary
    Predicted to be involved in mitochondrial proton-transporting ATP synthase complex assembly. Predicted to be located in mitochondrial matrix. Predicted to be active in mitochondrion. Is expressed in adult heart. Orthologous to human ATPAF1 (ATP synthase mitochondrial F1 complex assembly factor 1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG10340 in Genome Data Viewer
    Location:
    89D5-89D5; 3-59 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (16613398..16614391, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (12439120..12440113, complement)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene neuropeptide F Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene mir-2494 stem loop

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The Drosophila gene 2A5 complements the defect in mitochondrial F1-ATPase assembly in yeast lacking the molecular chaperone Atp11p. Wang ZG, et al. FEBS Lett, 1999 Jun 11. PMID 10386611
    2. Heterochromatin protein 1 (HP1a) positively regulates euchromatic gene expression through RNA transcript association and interaction with hnRNPs in Drosophila. Piacentini L, et al. PLoS Genet, 2009 Oct. PMID 19798443, Free PMC Article
    3. Chromosome-wide gene-specific targeting of the Drosophila dosage compensation complex. Gilfillan GD, et al. Genes Dev, 2006 Apr 1. PMID 16547172, Free PMC Article
    4. A screen for fast evolving genes from Drosophila. Schmid KJ, et al. Proc Natl Acad Sci U S A, 1997 Sep 2. PMID 9275195, Free PMC Article
    5. Transcriptome analysis of FOXO-dependent hypoxia gene expression identifies Hipk as a regulator of low oxygen tolerance in Drosophila. Ding K, et al. G3 (Bethesda), 2022 Dec 1. PMID 36200850, Free PMC Article

    See all (31) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Process Evidence Code Pubs
    involved_in mitochondrial proton-transporting ATP synthase complex assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in mitochondrial proton-transporting ATP synthase complex assembly ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in mitochondrion organization ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in protein-containing complex assembly IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in mitochondrial matrix ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG10340-PA
    anon-fast-evolving-2A5

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      16613398..16614391 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_142308.2 → NP_650565.2  uncharacterized protein Dmel_CG10340 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_650565.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      O16050, Q9VES8
      Related
      FBpp0082803
      Conserved Domains (1) summary
      pfam06644
      Location:29 → 271
      ATP11; ATP11 protein
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O16050 O16050
    Q95SB2 Q95SB2
    Q9VES8 Q9VES8

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