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    Prp31 Pre-mRNA processing factor 31 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 39655, updated on 9-Dec-2024

    Summary

    Official Symbol
    Prp31provided by FlyBase
    Official Full Name
    Pre-mRNA processing factor 31provided by FlyBase
    Primary source
    FLYBASE:FBgn0036487
    Locus tag
    Dmel_CG6876
    See related
    AllianceGenome:FB:FBgn0036487
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    anon-EST:Liang-2.38; CG6876; clone 2.38; Dmel\CG6876; FBgn0036487; prp31
    Summary
    Predicted to enable RNA binding activity and ribonucleoprotein complex binding activity. Predicted to be involved in mRNA splicing, via spliceosome. Part of precatalytic spliceosome. Is expressed in organism. Used to study retinitis pigmentosa and retinitis pigmentosa 11. Human ortholog(s) of this gene implicated in retinitis pigmentosa 11. Orthologous to human PRPF31 (pre-mRNA processing factor 31). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Prp31 in Genome Data Viewer
    Location:
    71B6-71B6; 3-42 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (15159100..15161138)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (15152200..15154238)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene Peroxin 3 Neighboring gene alpha1,3-fucosyltransferase A Neighboring gene Msh6 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR44562

    Genomic regions, transcripts, and products

    Bibliography

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables RNA binding ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    enables ribonucleoprotein complex binding ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Process Evidence Code Pubs
    involved_in mRNA splicing, via spliceosome IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in mRNA splicing, via spliceosome IC
    Inferred by Curator
    more info
    PubMed 
    involved_in mRNA splicing, via spliceosome IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in mRNA splicing, via spliceosome ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    involved_in spliceosomal tri-snRNP complex assembly IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    part_of U4 snRNP IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of U4/U6 x U5 tri-snRNP complex IEA
    Inferred from Electronic Annotation
    more info
     
    part_of precatalytic spliceosome HDA PubMed 
    part_of precatalytic spliceosome IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of spliceosomal complex ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    part_of spliceosomal tri-snRNP complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    Pre-mRNA processing factor 31
    Names
    CG6876-PA
    Prp31-PA

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      15159100..15161138
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_140499.3NP_648756.1  Pre-mRNA processing factor 31 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_648756.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VUM1
      Related
      FBpp0075395
      Conserved Domains (3) summary
      smart00931
      Location:101152
      NOSIC; NOSIC (NUC001) domain
      pfam01798
      Location:107337
      Nop; snoRNA binding domain, fibrillarin
      pfam09785
      Location:345472
      Prp31_C; Prp31 C terminal domain