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    Rpl37rt ribosomal protein L37, retrotransposed [ Mus musculus (house mouse) ]

    Gene ID: 100502825, updated on 27-Nov-2024

    Summary

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    Official Symbol
    Rpl37rtprovided by MGI
    Official Full Name
    ribosomal protein L37, retrotransposedprovided by MGI
    Primary source
    MGI:MGI:3651519
    See related
    Ensembl:ENSMUSG00000121818 AllianceGenome:MGI:3651519
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Rpl37; Gm13826; EyeLinc4
    Summary
    Predicted to enable MDM2/MDM4 family protein binding activity; growth factor binding activity; and ubiquitin ligase inhibitor activity. Predicted to be a structural constituent of ribosome. Predicted to be involved in positive regulation of signal transduction by p53 class mediator. Predicted to be located in cytosolic ribosome. Predicted to be part of cytosolic large ribosomal subunit. Orthologous to human RPL37 (ribosomal protein L37). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Ubiquitous expression in liver E14 (RPKM 408.1), CNS E11.5 (RPKM 382.4) and 28 other tissues See more
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    Genomic context

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    See Rpl37rt in Genome Data Viewer
    Location:
    5 F; 5 55.99 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (115240981..115248327, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (115102922..115110268, complement)

    Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene HNF1 homeobox A Neighboring gene STARR-seq mESC enhancer starr_14093 Neighboring gene HNF1 homeobox A, opposite strand 1 Neighboring gene STARR-seq mESC enhancer starr_14096 Neighboring gene signal peptide peptidase 3 Neighboring gene STARR-seq mESC enhancer starr_14098 Neighboring gene STARR-seq mESC enhancer starr_14099 Neighboring gene predicted gene, 54336 Neighboring gene acyl-Coenzyme A dehydrogenase, short chain Neighboring gene STARR-positive B cell enhancer ABC_E10342 Neighboring gene unc-119 lipid binding chaperone B

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Evolutionarily conserved long intergenic non-coding RNAs in the eye. Mustafi D, et al. Hum Mol Genet, 2013 Aug 1. PMID 23562822, Free PMC Article
    2. Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors. Kim H, et al. Cell, 2018 Dec 13. PMID 30550785, Free PMC Article
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334, Free PMC Article
    4. The transcriptional landscape of the mammalian genome. Carninci P, et al. Science, 2005 Sep 2. PMID 16141072

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables MDM2/MDM4 family protein binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables growth factor binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables structural constituent of ribosome ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables ubiquitin ligase inhibitor activity ISO
    Inferred from Sequence Orthology
    more info
    		  
    Process Evidence Code Pubs
    involved_in positive regulation of signal transduction by p53 class mediator ISO
    Inferred from Sequence Orthology
    more info
    		  
    Component Evidence Code Pubs
    part_of cytosolic large ribosomal subunit ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in cytosolic ribosome ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    large ribosomal subunit protein eL37
    Names
    60S ribosomal protein L37

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001271590.1 → NP_001258519.1  large ribosomal subunit protein eL37

      See identical proteins and their annotated locations for NP_001258519.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript. Both variants 1 and 2 encode the same protein.
      Source sequence(s)
      AC119205
      UniProtKB/Swiss-Prot
      Q6ZWV1, Q9D823
      Related
      ENSMUST00000100847.5
      Conserved Domains (1) summary
      PTZ00073
      Location:1 → 88
      PTZ00073; 60S ribosomal protein L37; Provisional

    2. NM_001271591.1 → NP_001258520.1  large ribosomal subunit protein eL37

      See identical proteins and their annotated locations for NP_001258520.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR, compared to variant 1. Both variants 1 and 2 encode the same protein.
      Source sequence(s)
      AC119205, BB707379
      UniProtKB/Swiss-Prot
      Q6ZWV1, Q9D823
      Conserved Domains (1) summary
      PTZ00073
      Location:1 → 88
      PTZ00073; 60S ribosomal protein L37; Provisional

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000071.7 Reference GRCm39 C57BL/6J

      Range
      115240981..115248327 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9D823.3 GenPept UniProtKB/Swiss-Prot:Q9D823

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