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    Rrp1b ribosomal RNA processing 1B [ Rattus norvegicus (Norway rat) ]

    Gene ID: 309673, updated on 9-Dec-2024

    Summary

    Official Symbol
    Rrp1bprovided by RGD
    Official Full Name
    ribosomal RNA processing 1Bprovided by RGD
    Primary source
    RGD:1305633
    See related
    EnsemblRapid:ENSRNOG00000001194 AllianceGenome:RGD:1305633
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1305633
    Summary
    Predicted to enable transcription coactivator activity. Predicted to be involved in several processes, including cellular response to virus; negative regulation of GTPase activity; and regulation of gene expression. Predicted to be located in chromatin and nuclear lumen. Predicted to be part of preribosome, small subunit precursor. Predicted to be active in nucleus. Orthologous to human RRP1B (ribosomal RNA processing 1B). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Thymus (RPKM 43.3), Spleen (RPKM 40.4) and 9 other tissues See more
    Orthologs
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    Genomic context

    See Rrp1b in Genome Data Viewer
    Location:
    20p12
    Exon count:
    17
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 20 NC_086038.1 (10122825..10148404)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 20 NC_051355.1 (10123111..10148704)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 20 NC_005119.4 (10844234..10869830)

    Chromosome 20 - NC_086038.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC120098852 Neighboring gene heat shock transcription factor 2 binding protein Neighboring gene pyridoxal kinase like 1 Neighboring gene pyridoxal kinase

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Gene Ontology Provided by RGD

    Component Evidence Code Pubs
    located_in chromosome  
    located_in euchromatin  
    located_in granular component  
    located_in heterochromatin  
    located_in nucleolus  
    located_in nucleoplasm  
    located_in nucleoplasm  
    is_active_in nucleus  
    located_in nucleus  
    part_of preribosome, small subunit precursor  

    General protein information

    Preferred Names
    ribosomal RNA processing protein 1 homolog B
    Names
    ribosomal RNA processing 1 homolog B

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001427282.1NP_001414211.1  ribosomal RNA processing protein 1 homolog B

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000020
      Related
      ENSRNOP00000001583.8, ENSRNOT00000001583.9

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086038.1 Reference GRCr8

      Range
      10122825..10148404
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017601874.3XP_017457363.1  ribosomal RNA processing protein 1 homolog B isoform X1

      UniProtKB/TrEMBL
      D3ZY39
      Conserved Domains (1) summary
      pfam05997
      Location:2148
      Nop52; Nucleolar protein,Nop52
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