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    IL17RC interleukin 17 receptor C [ Homo sapiens (human) ]

    Gene ID: 84818, updated on 10-Dec-2024

    Summary

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    Official Symbol
    IL17RCprovided by HGNC
    Official Full Name
    interleukin 17 receptor Cprovided by HGNC
    Primary source
    HGNC:HGNC:18358
    See related
    Ensembl:ENSG00000163702 MIM:610925; AllianceGenome:HGNC:18358
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    CANDF9; IL17RL; IL17-RL
    Summary
    This gene encodes a single-pass type I membrane protein that shares similarity with the interleukin-17 receptor (IL-17RA). Unlike IL-17RA, which is predominantly expressed in hemopoietic cells, and binds with high affinity to only IL-17A, this protein is expressed in nonhemopoietic tissues, and binds both IL-17A and IL-17F with similar affinities. The proinflammatory cytokines, IL-17A and IL-17F, have been implicated in the progression of inflammatory and autoimmune diseases. Multiple alternatively spliced transcript variants encoding different isoforms have been detected for this gene, and it has been proposed that soluble, secreted proteins lacking transmembrane and intracellular domains may function as extracellular antagonists to cytokine signaling. [provided by RefSeq, Feb 2011]
    Expression
    Ubiquitous expression in prostate (RPKM 15.4), skin (RPKM 9.6) and 25 other tissues See more
    Orthologs
    mouse all
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    Genomic context

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    See IL17RC in Genome Data Viewer
    Location:
    3p25.3; 3p25.3-p24.1
    Exon count:
    19
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 3 NC_000003.12 (9917098..9933621)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 3 NC_060927.1 (9909121..9925611)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 3 NC_000003.11 (9958782..9975305)

    Chromosome 3 - NC_000003.12Genomic Context describing neighboring genes Neighboring gene jagunal homolog 1 Neighboring gene Sharpr-MPRA regulatory region 14744 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr3:9944736-9945405 Neighboring gene interleukin 17 receptor E Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 14047 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 14048 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 14049 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr3:9958035-9958574 Neighboring gene RNA, U6 small nuclear 882, pseudogene Neighboring gene H3K4me1 hESC enhancer GRCh37_chr3:9970047-9970546 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 14050 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 14051 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 19413 Neighboring gene cysteine rich with EGF like domains 1 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr3:9980935-9981732 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr3:9987356-9988018 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr3:9988681-9989342 Neighboring gene PRRT3 antisense RNA 1 Neighboring gene 3p25 PRRT3 Alu-mediated recombination region Neighboring gene proline rich transmembrane protein 3 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 14052

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

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    Related articles in PubMed

    1. Associations of Common Genetic Variants on IL-17 Genes and Carotid Intima-Media Thickness. Wu TW, et al. J Atheroscler Thromb, 2018 Nov 1. PMID 29695654, Free PMC Article
    2. A single-nucleotide polymorphism rs708567 in the IL-17RC gene is associated with a susceptibility to and the curve severity of adolescent idiopathic scoliosis in a Chinese Han population: a case-control study. Zhou S, et al. BMC Musculoskelet Disord, 2012 Sep 21. PMID 22999050, Free PMC Article
    3. Overexpression of IL-17RC associated with ocular sarcoidosis. Wu W, et al. J Transl Med, 2014 May 31. PMID 24885153, Free PMC Article
    4. Inherited IL-17RC deficiency in patients with chronic mucocutaneous candidiasis. Ling Y, et al. J Exp Med, 2015 May 4. PMID 25918342, Free PMC Article
    5. Probable Chemical Hypoxia Effects on Progress of CNV Through Induction of Promoter CpG Demethylation and Overexpression of IL17RC in Human RPE Cells. Alivand MR, et al. Curr Eye Res, 2016 Sep. PMID 26731132

    See all (38) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Associations of IL-17 and IL-17 receptor polymorphisms with Behcet's disease in Denizli Province of Turkey.
      Title: Associations of IL-17 and IL-17 receptor polymorphisms with Behçet's disease in Denizli Province of Turkey.
    2. IL-17A promotes Helicobacter pylori-induced gastric carcinogenesis via interactions with IL-17RC.
      Title: IL-17A promotes Helicobacter pylori-induced gastric carcinogenesis via interactions with IL-17RC.
    3. IL-17 Receptor C Signaling Controls CD4(+) TH17 Immune Responses and Tissue Injury in Immune-Mediated Kidney Diseases.
      Title: IL-17 Receptor C Signaling Controls CD4(+) T(H)17 Immune Responses and Tissue Injury in Immune-Mediated Kidney Diseases.
    4. Interleukin-17 receptor C gene polymorphism reduces treatment effect and promotes poor prognosis of ischemic stroke.
      Title: Interleukin-17 receptor C gene polymorphism reduces treatment effect and promotes poor prognosis of ischemic stroke.
    5. The crystal structure of the interleukin 17 receptor C (IL-17RC):interleukin 17F (IL-17F) complex provides a structural basis for IL-17F signaling through IL-17RC.
      Title: Structural Analysis Reveals that the Cytokine IL-17F Forms a Homodimeric Complex with Receptor IL-17RC to Drive IL-17RA-Independent Signaling.
    6. An increase in IL17RC gene expression levels in peripheral blood samples was found in ossification of the posterior longitudinal ligament patients.
      Title: IL17RC affects the predisposition to thoracic ossification of the posterior longitudinal ligament.
    7. Genetic study revealed no association between IL-17RC, and SNPs and acute kidney transplant graft rejection. Nevertheless, a significant improvement of graft survival was found in kidney transplant recipients carrying the IL-17RC*G/G, and *G/A genotypes.
      Title: The role of IL-23/IL-17 axis in human kidney allograft rejection.
    8. Genetic Variants on IL-17 are associated with development of atherosclerotic diseases.
      Title: Associations of Common Genetic Variants on IL-17 Genes and Carotid Intima-Media Thickness.
    9. Five SNPs in the IL17RC (and COL6A1) genes were found to be associated with susceptibility to ossification of the posterior longitudinal ligament in Han Chinese patients.
      Title: Association of IL17RC and COL6A1 genetic polymorphisms with susceptibility to ossification of the thoracic posterior longitudinal ligament in Chinese patients.
    10. IL-17RC rs708567 polymorphism in A/A genotype, G/G genotype, and G/a genotype did not seem to influence RA susceptibility in Tunisian population.
      Title: IL-17A, IL-17RC polymorphisms and IL17 plasma levels in Tunisian patients with rheumatoid arthritis.
    Submit: New GeneRIF Correction See all GeneRIFs (23)

    Phenotypes

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    Find tests for this gene in the NIH Genetic Testing Registry (GTR)

    Review eQTL and phenotype association data in this region using PheGenI

    Associated conditions

    Description Tests
    Candidiasis, familial, 9
    MedGen: C4225324 OMIM: 616445 GeneReviews: Not available
    		Compare labs

    Variation

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    See variants in ClinVar

    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    See Variation Viewer (GRCh38)

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Clone Names

    • FLJ95963, FLJ96005, MGC10763

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables coreceptor activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables interleukin-17 receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables interleukin-17 receptor activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables signaling receptor binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in defense response to fungus IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in granulocyte chemotaxis IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in inflammatory response IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in interleukin-17A-mediated signaling pathway IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in positive regulation of cytokine production involved in inflammatory response IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in positive regulation of interleukin-6 production IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cell surface IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in plasma membrane IC
    Inferred by Curator
    more info
    		 PubMed 
    located_in plasma membrane TAS
    Traceable Author Statement
    more info
    		  

    General protein information

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    Preferred Names
    interleukin-17 receptor C
    Names
    IL-17 receptor C
    IL-17RL
    IL17F receptor
    IL17Rhom
    interleukin-17 receptor homolog
    interleukin-17 receptor-like protein
    zcytoR14

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    Genomic

    1. NG_029376.2 RefSeqGene

      Range
      5001..21524
      Download
      GenBank, FASTA, Sequence Viewer (Graphics), LRG_1311

    mRNA and Protein(s)

    1. NM_001203263.2 → NP_001190192.2  interleukin-17 receptor C isoform 4 precursor

      Status: REVIEWED

      Description
      Transcript Variant: This variant (4) lacks the penultimate coding exon compared to variant 1, however, maintains the reading frame. This results in a shorter isoform (4) missing a protein segment in the C-terminal region compared to isoform 1.
      Source sequence(s)
      AC018809
      Consensus CDS
      CCDS56240.1
      UniProtKB/TrEMBL
      A0A8Q3SJ19
      Related
      ENSP00000396064.1, ENST00000413608.2
      Conserved Domains (2) summary
      pfam08357
      Location:506 → 653
      SEFIR; SEFIR domain
      pfam15037
      Location:71 → 459
      IL17_R_N; Interleukin-17 receptor extracellular region

    2. NM_001203264.2 → NP_001190193.2  interleukin-17 receptor C isoform 5 precursor

      Status: REVIEWED

      Description
      Transcript Variant: This variant (5) lacks 2 in-frame coding exons (exon 12 and penultimate exon) compared to variant 1, resulting in a shorter isoform (5, also known as IL-17RCdelta12) missing 2 internal protein segments compared to isoform 1. It has been reported that isoforms lacking exon 12 lose the ability to bind cytokines, IL-17A and IL-17F (PMID:17911633).
      Source sequence(s)
      AC018809
      Consensus CDS
      CCDS74898.1
      UniProtKB/TrEMBL
      A0A8Q3SIU5
      Related
      ENSP00000395315.3, ENST00000416074.6
      Conserved Domains (3) summary
      pfam08357
      Location:489 → 636
      SEFIR; SEFIR domain
      pfam15037
      Location:71 → 442
      IL17_R_N; Interleukin-17 receptor extracellular region
      pfam17243
      Location:632 → 668
      POTRA_TamA_1; POTRA domain TamA domain 1

    3. NM_001203265.2 → NP_001190194.2  interleukin-17 receptor C isoform 6 precursor

      Status: REVIEWED

      Description
      Transcript Variant: This variant (6) lacks 2 in-frame coding exons (exons 7 and 12) compared to variant 1, resulting in a shorter isoform (6, also known as IL-17RCdelta7,12) missing 2 internal protein segments compared to isoform 1. It has been reported that isoforms lacking exon 12 lose the ability to bind cytokines, IL-17A and IL-17F (PMID:17911633).
      Source sequence(s)
      AC018809
      Consensus CDS
      CCDS56241.1
      UniProtKB/TrEMBL
      A0A8Q3SIU5
      Related
      ENSP00000407894.1, ENST00000455057.5
      Conserved Domains (2) summary
      pfam08357
      Location:487 → 634
      SEFIR; SEFIR domain
      pfam15037
      Location:71 → 427
      IL17_R_N; Interleukin-17 receptor extracellular region

    4. NM_001367278.1 → NP_001354207.1  interleukin-17 receptor C isoform 7 precursor

      Status: REVIEWED

      Source sequence(s)
      AC018809
      Consensus CDS
      CCDS93201.1
      UniProtKB/TrEMBL
      A0A8Q3SIV5, A0A8Q3SJJ9
      Related
      ENSP00000512902.1, ENST00000696824.1
      Conserved Domains (2) summary
      pfam08357
      Location:493 → 640
      SEFIR; SEFIR domain
      pfam15037
      Location:71 → 446
      IL17_R_N; Interleukin-17 receptor extracellular region

    5. NM_001367279.1 → NP_001354208.1  interleukin-17 receptor C isoform 8 precursor

      Status: REVIEWED

      Source sequence(s)
      AC018809
      UniProtKB/TrEMBL
      A0A8Q3WM30
      Conserved Domains (2) summary
      pfam08357
      Location:466 → 613
      SEFIR; SEFIR domain
      pfam15037
      Location:71 → 419
      IL17_R_N; Interleukin-17 receptor extracellular region

    6. NM_001367280.1 → NP_001354209.1  interleukin-17 receptor C isoform 9 precursor

      Status: REVIEWED

      Source sequence(s)
      AC018809
      Consensus CDS
      CCDS93202.1
      UniProtKB/TrEMBL
      A0A8Q3SJ19
      Related
      ENSP00000512897.1, ENST00000696816.1
      Conserved Domains (2) summary
      pfam08357
      Location:491 → 638
      SEFIR; SEFIR domain
      pfam15037
      Location:71 → 444
      IL17_R_N; Interleukin-17 receptor extracellular region

    7. NM_001410711.1 → NP_001397640.1  interleukin-17 receptor C isoform 10 precursor

      Status: REVIEWED

      Source sequence(s)
      AC018809
      Consensus CDS
      CCDS93203.1
      UniProtKB/TrEMBL
      A0A8Q3SIU5, A0A8Q3SJ01
      Related
      ENSP00000512904.1, ENST00000696826.1

    8. NM_032732.6 → NP_116121.3  interleukin-17 receptor C isoform 3 precursor

      Status: REVIEWED

      Description
      Transcript Variant: This variant (3) lacks an in-frame coding exon (exon 7) compared to variant 1, resulting in a shorter isoform (3, also known as IL-17RCdelta7) missing an internal protein segment compared to isoform 1. It has been reported that isoform lacking exon 7 retains the ability to bind cytokines, IL-17A and IL-17F (PMID:17911633).
      Source sequence(s)
      AC018809
      Consensus CDS
      CCDS2591.2
      UniProtKB/TrEMBL
      A0A8Q3SJ19
      Related
      ENSP00000373323.4, ENST00000383812.9
      Conserved Domains (2) summary
      pfam08357
      Location:504 → 651
      SEFIR; SEFIR domain
      pfam15037
      Location:71 → 444
      IL17_R_N; Interleukin-17 receptor extracellular region

    9. NM_153460.4 → NP_703190.2  interleukin-17 receptor C isoform 1 precursor

      Status: REVIEWED

      Description
      Transcript Variant: This variant (1) represents the predominant transcript containing all the coding exons, and encodes isoform 1 (also known as IL-17RCFL).
      Source sequence(s)
      AC018809, AF458065, AK096824, AK225650, AY358840, DC381087
      Consensus CDS
      CCDS46746.1
      UniProtKB/TrEMBL
      A0A8Q3SJ19
      Related
      ENSP00000384969.3, ENST00000403601.8
      Conserved Domains (2) summary
      pfam08357
      Location:519 → 666
      SEFIR; SEFIR domain
      pfam15037
      Location:71 → 459
      IL17_R_N; Interleukin-17 receptor extracellular region

    10. NM_153461.4 → NP_703191.2  interleukin-17 receptor C isoform 2 precursor

      Status: REVIEWED

      Description
      Transcript Variant: This variant (2) uses an alternate donor splice site at the 5' terminal coding exon compared to variant 1, resulting in a longer isoform (2) containing an additional protein segment compared to isoform 1.
      Source sequence(s)
      AC018809
      Consensus CDS
      CCDS2590.1
      UniProtKB/Swiss-Prot
      A8BWC1, A8BWC9, A8BWD5, E9PHG1, E9PHJ6, Q6UVY3, Q6UWD4, Q8NAC3, Q8NFS1, Q9BR97
      UniProtKB/TrEMBL
      A0A8Q3SJ19
      Related
      ENSP00000295981.3, ENST00000295981.7
      Conserved Domains (2) summary
      pfam08357
      Location:590 → 737
      SEFIR; SEFIR domain
      pfam15037
      Location:142 → 530
      IL17_R_N; Interleukin-17 receptor extracellular region

    RNA

    1. NR_037807.2 RNA Sequence

      Status: REVIEWED

      Description
      Transcript Variant: This variant (7) lacks exon 7 and is alternatively spliced in the mid-coding region compared to variant 1. It is represented as non-coding because the use of the 5'-most translational start codon as used in variant 1, renders this transcript a candidate for nonsense-mediated mRNA decay (NMD).
      Source sequence(s)
      AC018809
      Related
      ENST00000466046.5

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000003.12 Reference GRCh38.p14 Primary Assembly

      Range
      9917098..9933621
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017007326.1 → XP_016862815.1  interleukin-17 receptor C isoform X1

      UniProtKB/TrEMBL
      A0A8Q3SJ19

    2. XM_017007327.2 → XP_016862816.1  interleukin-17 receptor C isoform X2

      UniProtKB/TrEMBL
      A0A8Q3SJ19

    3. XM_017007329.2 → XP_016862818.1  interleukin-17 receptor C isoform X4

      UniProtKB/TrEMBL
      A0A8Q3SJ19

    4. XM_017007333.1 → XP_016862822.1  interleukin-17 receptor C isoform X8

      UniProtKB/TrEMBL
      A0A8Q3SIU5

    5. XM_017007336.2 → XP_016862825.1  interleukin-17 receptor C isoform X12

      UniProtKB/TrEMBL
      A0A8Q3SIU5

    6. XM_017007328.1 → XP_016862817.1  interleukin-17 receptor C isoform X3

      UniProtKB/TrEMBL
      A0A8Q3SJJ9

    7. XM_017007330.1 → XP_016862819.1  interleukin-17 receptor C isoform X5

      UniProtKB/TrEMBL
      A0A8Q3SJJ9

    8. XM_017007331.1 → XP_016862820.1  interleukin-17 receptor C isoform X6

      UniProtKB/TrEMBL
      A0A8Q3SJ19

    9. XM_017007332.1 → XP_016862821.1  interleukin-17 receptor C isoform X7

      UniProtKB/TrEMBL
      A0A8Q3SJ19

    10. XM_024453793.2 → XP_024309561.1  interleukin-17 receptor C isoform X10

      UniProtKB/TrEMBL
      A0A8Q3SJ19
      Conserved Domains (2) summary
      pfam08357
      Location:562 → 709
      SEFIR; SEFIR domain
      pfam15037
      Location:142 → 515
      IL17_R_N; Interleukin-17 receptor extracellular region

    11. XM_047449066.1 → XP_047305022.1  interleukin-17 receptor C isoform X13

      UniProtKB/TrEMBL
      A0A8Q3SIU5

    12. XM_017007339.2 → XP_016862828.1  interleukin-17 receptor C isoform X16

      UniProtKB/TrEMBL
      A0A8Q3SIU5

    13. XM_017007335.1 → XP_016862824.1  interleukin-17 receptor C isoform X11

      UniProtKB/TrEMBL
      A0A8Q3SJ19

    14. XM_017007338.2 → XP_016862827.1  interleukin-17 receptor C isoform X15

      UniProtKB/TrEMBL
      A0A8Q3SJ19

    15. XM_024453794.1 → XP_024309562.1  interleukin-17 receptor C isoform X17

      UniProtKB/TrEMBL
      A0A8Q3SIU5
      Conserved Domains (2) summary
      pfam08357
      Location:545 → 692
      SEFIR; SEFIR domain
      pfam15037
      Location:142 → 485
      IL17_R_N; Interleukin-17 receptor extracellular region

    16. XM_017007334.1 → XP_016862823.1  interleukin-17 receptor C isoform X9

      UniProtKB/TrEMBL
      A0A8Q3WM30

    17. XM_017007337.1 → XP_016862826.1  interleukin-17 receptor C isoform X14

      UniProtKB/TrEMBL
      A0A8Q3WM30

    18. XM_047449067.1 → XP_047305023.1  interleukin-17 receptor C isoform X19

      UniProtKB/TrEMBL
      A0A8Q3SIU5

    19. XM_017007340.2 → XP_016862829.1  interleukin-17 receptor C isoform X18

      UniProtKB/TrEMBL
      A0A8Q3SJ19

    20. XM_047449068.1 → XP_047305024.1  interleukin-17 receptor C isoform X20

      UniProtKB/TrEMBL
      A0A8Q3SJ19

    21. XM_047449070.1 → XP_047305026.1  interleukin-17 receptor C isoform X23

      UniProtKB/TrEMBL
      A0A8Q3SIU5

    22. XM_047449069.1 → XP_047305025.1  interleukin-17 receptor C isoform X21

      UniProtKB/TrEMBL
      A0A8Q3SJJ9

    23. XM_017007341.2 → XP_016862830.1  interleukin-17 receptor C isoform X22

      UniProtKB/TrEMBL
      A0A8Q3SJ19

    24. XM_047449071.1 → XP_047305027.1  interleukin-17 receptor C isoform X26

      UniProtKB/TrEMBL
      A0A8Q3SJ19

    25. XM_017007345.2 → XP_016862834.1  interleukin-17 receptor C isoform X27

      UniProtKB/TrEMBL
      A0A8Q3SJ19

    26. XM_047449072.1 → XP_047305028.1  interleukin-17 receptor C isoform X28

      UniProtKB/TrEMBL
      A0A8Q3SJ19

    27. XM_047449075.1 → XP_047305031.1  interleukin-17 receptor C isoform X32

      UniProtKB/TrEMBL
      A0A8Q3SJ19

    28. XM_017007348.2 → XP_016862837.1  interleukin-17 receptor C isoform X33

      UniProtKB/TrEMBL
      A0A8Q3SIU5

    29. XM_017007342.1 → XP_016862831.1  interleukin-17 receptor C isoform X24

      UniProtKB/TrEMBL
      A0A8Q3WM30

    30. XM_017007343.1 → XP_016862832.1  interleukin-17 receptor C isoform X25

      UniProtKB/TrEMBL
      A0A8Q3WM30

    31. XM_047449073.1 → XP_047305029.1  interleukin-17 receptor C isoform X29

      UniProtKB/TrEMBL
      A0A8Q3WM30

    32. XM_017007347.1 → XP_016862836.1  interleukin-17 receptor C isoform X30

      UniProtKB/TrEMBL
      A0A8Q3WM30

    33. XM_047449077.1 → XP_047305033.1  interleukin-17 receptor C isoform X34

      UniProtKB/TrEMBL
      A0A8Q3WM30, C9JSZ3
      Related
      ENSP00000414609.2, ENST00000438091.6

    34. XM_047449074.1 → XP_047305030.1  interleukin-17 receptor C isoform X31

      UniProtKB/TrEMBL
      A0A8Q3WM30

    35. XM_047449079.1 → XP_047305035.1  interleukin-17 receptor C isoform X36

      UniProtKB/TrEMBL
      A0A8Q3SIU5

    36. XM_047449080.1 → XP_047305036.1  interleukin-17 receptor C isoform X37

      UniProtKB/TrEMBL
      A0A8Q3SIU5

    37. XM_047449078.1 → XP_047305034.1  interleukin-17 receptor C isoform X35

      UniProtKB/TrEMBL
      A0A8Q3WM30

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060927.1 Alternate T2T-CHM13v2.0

      Range
      9909121..9925611
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054348098.1 → XP_054204073.1  interleukin-17 receptor C isoform X1

      UniProtKB/TrEMBL
      A0A8Q3SJ19

    2. XM_054348099.1 → XP_054204074.1  interleukin-17 receptor C isoform X2

      UniProtKB/TrEMBL
      A0A8Q3SJ19

    3. XM_054348101.1 → XP_054204076.1  interleukin-17 receptor C isoform X4

      UniProtKB/TrEMBL
      A0A8Q3SJ19

    4. XM_054348105.1 → XP_054204080.1  interleukin-17 receptor C isoform X8

      UniProtKB/TrEMBL
      A0A8Q3SIU5

    5. XM_054348109.1 → XP_054204084.1  interleukin-17 receptor C isoform X12

      UniProtKB/TrEMBL
      A0A8Q3SIU5

    6. XM_054348100.1 → XP_054204075.1  interleukin-17 receptor C isoform X3

      UniProtKB/TrEMBL
      A0A8Q3SJJ9

    7. XM_054348102.1 → XP_054204077.1  interleukin-17 receptor C isoform X5

      UniProtKB/TrEMBL
      A0A8Q3SJJ9

    8. XM_054348103.1 → XP_054204078.1  interleukin-17 receptor C isoform X6

      UniProtKB/TrEMBL
      A0A8Q3SJ19

    9. XM_054348104.1 → XP_054204079.1  interleukin-17 receptor C isoform X7

      UniProtKB/TrEMBL
      A0A8Q3SJ19

    10. XM_054348107.1 → XP_054204082.1  interleukin-17 receptor C isoform X10

      UniProtKB/TrEMBL
      A0A8Q3SJ19

    11. XM_054348110.1 → XP_054204085.1  interleukin-17 receptor C isoform X13

      UniProtKB/TrEMBL
      A0A8Q3SIU5

    12. XM_054348113.1 → XP_054204088.1  interleukin-17 receptor C isoform X16

      UniProtKB/TrEMBL
      A0A8Q3SIU5

    13. XM_054348108.1 → XP_054204083.1  interleukin-17 receptor C isoform X11

      UniProtKB/TrEMBL
      A0A8Q3SJ19

    14. XM_054348112.1 → XP_054204087.1  interleukin-17 receptor C isoform X15

      UniProtKB/TrEMBL
      A0A8Q3SJ19

    15. XM_054348114.1 → XP_054204089.1  interleukin-17 receptor C isoform X17

      UniProtKB/TrEMBL
      A0A8Q3SIU5

    16. XM_054348106.1 → XP_054204081.1  interleukin-17 receptor C isoform X9

      UniProtKB/TrEMBL
      A0A8Q3WM30

    17. XM_054348111.1 → XP_054204086.1  interleukin-17 receptor C isoform X14

      UniProtKB/TrEMBL
      A0A8Q3WM30

    18. XM_054348116.1 → XP_054204091.1  interleukin-17 receptor C isoform X19

      UniProtKB/TrEMBL
      A0A8Q3SIU5

    19. XM_054348115.1 → XP_054204090.1  interleukin-17 receptor C isoform X18

      UniProtKB/TrEMBL
      A0A8Q3SJ19

    20. XM_054348117.1 → XP_054204092.1  interleukin-17 receptor C isoform X20

      UniProtKB/TrEMBL
      A0A8Q3SJ19

    21. XM_054348120.1 → XP_054204095.1  interleukin-17 receptor C isoform X23

      UniProtKB/TrEMBL
      A0A8Q3SIU5

    22. XM_054348118.1 → XP_054204093.1  interleukin-17 receptor C isoform X21

      UniProtKB/TrEMBL
      A0A8Q3SJJ9

    23. XM_054348119.1 → XP_054204094.1  interleukin-17 receptor C isoform X22

      UniProtKB/TrEMBL
      A0A8Q3SJ19

    24. XM_054348123.1 → XP_054204098.1  interleukin-17 receptor C isoform X26

      UniProtKB/TrEMBL
      A0A8Q3SJ19

    25. XM_054348124.1 → XP_054204099.1  interleukin-17 receptor C isoform X27

      UniProtKB/TrEMBL
      A0A8Q3SJ19

    26. XM_054348125.1 → XP_054204100.1  interleukin-17 receptor C isoform X28

      UniProtKB/TrEMBL
      A0A8Q3SJ19

    27. XM_054348129.1 → XP_054204104.1  interleukin-17 receptor C isoform X32

      UniProtKB/TrEMBL
      A0A8Q3SJ19

    28. XM_054348130.1 → XP_054204105.1  interleukin-17 receptor C isoform X33

      UniProtKB/TrEMBL
      A0A8Q3SIU5

    29. XM_054348121.1 → XP_054204096.1  interleukin-17 receptor C isoform X24

      UniProtKB/TrEMBL
      A0A8Q3WM30

    30. XM_054348122.1 → XP_054204097.1  interleukin-17 receptor C isoform X25

      UniProtKB/TrEMBL
      A0A8Q3WM30

    31. XM_054348126.1 → XP_054204101.1  interleukin-17 receptor C isoform X29

      UniProtKB/TrEMBL
      A0A8Q3WM30

    32. XM_054348127.1 → XP_054204102.1  interleukin-17 receptor C isoform X30

      UniProtKB/TrEMBL
      A0A8Q3WM30

    33. XM_054348131.1 → XP_054204106.1  interleukin-17 receptor C isoform X34

      UniProtKB/TrEMBL
      A0A8Q3WM30

    34. XM_054348128.1 → XP_054204103.1  interleukin-17 receptor C isoform X31

      UniProtKB/TrEMBL
      A0A8Q3WM30

    35. XM_054348133.1 → XP_054204108.1  interleukin-17 receptor C isoform X36

      UniProtKB/TrEMBL
      A0A8Q3SIU5

    36. XM_054348134.1 → XP_054204109.1  interleukin-17 receptor C isoform X37

      UniProtKB/TrEMBL
      A0A8Q3SIU5

    37. XM_054348132.1 → XP_054204107.1  interleukin-17 receptor C isoform X35

      UniProtKB/TrEMBL
      A0A8Q3WM30

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_153462.1: Suppressed sequence

      Description
      NM_153462.1: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript and the protein, and because it is a nonsense-mediated mRNA decay (NMD) candidate.

    2. NM_153463.1: Suppressed sequence

      Description
      NM_153463.1: This RefSeq was permanently suppressed because it is a nonsense-mediated mRNA decay (NMD) candidate.
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8NAC3.2 GenPept UniProtKB/Swiss-Prot:Q8NAC3

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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