NEW
Try the new Transcript table
These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
Genomic
-
NG_032907.2 RefSeqGene
- Range
-
5034..69275
- Download
- GenBank, FASTA, Sequence Viewer (Graphics), LRG_645
mRNA and Protein(s)
-
NM_001136528.2 → NP_001130000.1 glia-derived nexin isoform b precursor
See identical proteins and their annotated locations for NP_001130000.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (2) uses an alternate in-frame splice site in the 3' coding region, compared to variant 1, resulting in an isoform (b) that is 1 aa shorter than isoform a.
- Source sequence(s)
-
AC073641, AI754402, AK225823, DB325994
- Consensus CDS
-
CCDS46526.1
- UniProtKB/TrEMBL
-
B4DMR3
- Related
- ENSP00000386412.1, ENST00000409304.6
- Conserved Domains (1) summary
-
- cd19573
Location:21 → 395
- serpinE2_GDN; serpin family E member 2, glia derived nexin (GDN)
-
NM_001136530.1 → NP_001130002.1 glia-derived nexin isoform c precursor
See identical proteins and their annotated locations for NP_001130002.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (4) differs in the 5' UTR and 5' coding region, uses an alternate start codon, and uses an alternate in-frame splice site in the 3' coding region, compared to variant 1. The resulting isoform (c) has a distinct N-terminus and is longer than isoform a.
- Source sequence(s)
-
AI754402, AK295564, BX360097, DB325994, DC304261
- Consensus CDS
-
CCDS46525.1
- UniProtKB/TrEMBL
-
B4DMR3
- Related
- ENSP00000415786.2, ENST00000447280.6
- Conserved Domains (1) summary
-
- cd02051
Location:33 → 409
- PAI-1_nexin-1; Plasminogen activator inhibitor-1_like. Plasminogen activator inhibitor-1 (PAI-1) is the primary, fast-acting inhibitor of plasminogen activators. It is often bound to vitronectin, an abundant component of the extracellular matrix in many tissues. ...
-
NM_006216.4 → NP_006207.1 glia-derived nexin isoform a precursor
See identical proteins and their annotated locations for NP_006207.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (1) encodes isoform a.
- Source sequence(s)
-
AC073641
- Consensus CDS
-
CCDS2460.1
- UniProtKB/Swiss-Prot
- B2R6A4, B4DIF2, P07093, Q53S15, Q5D0C4
- UniProtKB/TrEMBL
-
B4DMR3
- Related
- ENSP00000258405.4, ENST00000258405.9
- Conserved Domains (1) summary
-
- cd02051
Location:21 → 398
- PAI-1_nexin-1; Plasminogen activator inhibitor-1_like. Plasminogen activator inhibitor-1 (PAI-1) is the primary, fast-acting inhibitor of plasminogen activators. It is often bound to vitronectin, an abundant component of the extracellular matrix in many tissues. ...
RNA
-
NR_073116.2 RNA Sequence
Status: REVIEWED
- Description
- Transcript Variant: This variant (3) has alternate 5' exon structure and uses an alternate splice site in an internal exon, compared to variant 1. This variant is represented as non-coding due to the presence of an upstream ORF that is predicted to interfere with translation of the downstream in-frame ORF. Translation of the upstream ORF renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
- Source sequence(s)
-
AC073641
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as
RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate
assemblies. Model RNAs and proteins are also reported here.
Reference GRCh38.p14 Primary Assembly
Genomic
-
NC_000002.12 Reference GRCh38.p14 Primary Assembly
- Range
-
223975045..224039286 complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_005246641.3 → XP_005246698.1 glia-derived nexin isoform X1
- UniProtKB/TrEMBL
-
B4DMR3
- Conserved Domains (1) summary
-
- cd19573
Location:33 → 408
- serpinE2_GDN; serpin family E member 2, glia derived nexin (GDN)
-
XM_017004330.2 → XP_016859819.1 glia-derived nexin isoform X2
- UniProtKB/Swiss-Prot
- B2R6A4, B4DIF2, P07093, Q53S15, Q5D0C4
- UniProtKB/TrEMBL
-
B4DMR3
- Conserved Domains (1) summary
-
- cd02051
Location:21 → 398
- PAI-1_nexin-1; Plasminogen activator inhibitor-1_like. Plasminogen activator inhibitor-1 (PAI-1) is the primary, fast-acting inhibitor of plasminogen activators. It is often bound to vitronectin, an abundant component of the extracellular matrix in many tissues. ...
-
XM_017004332.3 → XP_016859821.1 glia-derived nexin isoform X3
- UniProtKB/TrEMBL
-
B4DMR3
- Related
- ENSP00000386969.3, ENST00000409840.7
- Conserved Domains (1) summary
-
- cd19573
Location:21 → 395
- serpinE2_GDN; serpin family E member 2, glia derived nexin (GDN)
Alternate T2T-CHM13v2.0
Genomic
-
NC_060926.1 Alternate T2T-CHM13v2.0
- Range
-
224458312..224522521 complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_054342563.1 → XP_054198538.1 glia-derived nexin isoform X1
- UniProtKB/TrEMBL
-
B4DMR3
-
XM_054342564.1 → XP_054198539.1 glia-derived nexin isoform X2
- UniProtKB/Swiss-Prot
- B2R6A4, B4DIF2, P07093, Q53S15, Q5D0C4
- UniProtKB/TrEMBL
-
B4DMR3
-
XM_054342565.1 → XP_054198540.1 glia-derived nexin isoform X3
- UniProtKB/TrEMBL
-
B4DMR3