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    Slc25a2 solute carrier family 25 member 2 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 291640, updated on 9-Dec-2024

    Summary

    Official Symbol
    Slc25a2provided by RGD
    Official Full Name
    solute carrier family 25 member 2provided by RGD
    Primary source
    RGD:1310667
    See related
    EnsemblRapid:ENSRNOG00000020024 AllianceGenome:RGD:1310667
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable L-arginine transmembrane transporter activity; L-lysine transmembrane transporter activity; and L-ornithine transmembrane transporter activity. Predicted to be involved in L-alpha-amino acid transmembrane transport and ornithine metabolic process. Predicted to be located in membrane. Predicted to be active in mitochondrion. Orthologous to human SLC25A2 (solute carrier family 25 member 2). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See Slc25a2 in Genome Data Viewer
    Location:
    18p11
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 18 NC_086036.1 (29704182..29707563, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 18 NC_051353.1 (29452943..29456324, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 18 NC_005117.4 (30774205..30775401, complement)

    Chromosome 18 - NC_086036.1Genomic Context describing neighboring genes Neighboring gene protocadherin beta 22 Neighboring gene ferritin light chain 1, pseudogene 3 Neighboring gene TATA-box binding protein associated factor 7 Neighboring gene zinc finger protein 605 like 1 Neighboring gene protocadherin gamma subfamily A, 1 Neighboring gene protocadherin gamma subfamily A, 2 Neighboring gene protocadherin gamma subfamily A, 3 Neighboring gene protocadherin gamma subfamily B, 1

    Genomic regions, transcripts, and products

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables L-arginine transmembrane transporter activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables L-lysine transmembrane transporter activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables L-ornithine transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables L-ornithine transmembrane transporter activity ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    involved_in L-arginine transmembrane transport ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in L-lysine transmembrane transport ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in L-ornithine transmembrane transport ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in biological_process ND
    No biological Data available
    more info
     
    involved_in mitochondrial L-ornithine transmembrane transport IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in mitochondrial L-ornithine transmembrane transport ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in ornithine metabolic process ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in mitochondrial inner membrane IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in mitochondrion ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    mitochondrial ornithine transporter 2
    Names
    solute carrier family 25 (mitochondrial carrier, ornithine transporter) member 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001106152.2NP_001099622.1  mitochondrial ornithine transporter 2

      See identical proteins and their annotated locations for NP_001099622.1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000018
      UniProtKB/TrEMBL
      A0A8I6G8E8, A6J379
      Related
      ENSRNOP00000089967.2, ENSRNOT00000115666.2
      Conserved Domains (1) summary
      pfam00153
      Location:169260
      Mito_carr; Mitochondrial carrier protein

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086036.1 Reference GRCr8

      Range
      29704182..29707563 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)