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    Tas2r137 taste receptor, type 2, member 137 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 500089, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Tas2r137provided by RGD
    Official Full Name
    taste receptor, type 2, member 137provided by RGD
    Primary source
    RGD:1560602
    See related
    EnsemblRapid:ENSRNOG00000030413 AllianceGenome:RGD:1560602
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Tas2r3; RGD1560602
    Summary
    Predicted to enable bitter taste receptor activity. Predicted to be involved in detection of chemical stimulus involved in sensory perception of bitter taste. Predicted to be active in membrane. Orthologous to human TAS2R3 (taste 2 receptor member 3). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Kidney (RPKM 25.6), Thymus (RPKM 20.6) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Tas2r137 in Genome Data Viewer
    Location:
    4q23
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 4 NC_086022.1 (70242964..70256215)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 4 NC_051339.1 (69279276..69286935)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 4 NC_005103.4 (68648296..68654695)

    Chromosome 4 - NC_086022.1Genomic Context describing neighboring genes Neighboring gene DENN domain containing 11 Neighboring gene WEE2 oocyte meiosis inhibiting kinase Neighboring gene single stranded DNA binding protein 1 Neighboring gene taste receptor, type 2, member 108 Neighboring gene serine protease 37 Neighboring gene olfactory receptor family 9 subfamily A member 7, pseudogene 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. The molecular receptive ranges of human TAS2R bitter taste receptors. Meyerhof W, et al. Chem Senses, 2010 Feb. PMID 20022913
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables G protein-coupled receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables bitter taste receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables bitter taste receptor activity ISO
    Inferred from Sequence Orthology
    more info
    		  
    Process Evidence Code Pubs
    involved_in G protein-coupled receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in detection of chemical stimulus involved in sensory perception of bitter taste IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in detection of chemical stimulus involved in sensory perception of bitter taste ISO
    Inferred from Sequence Orthology
    more info
    		  
    Component Evidence Code Pubs
    is_active_in membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    taste receptor type 2 member 3
    Names
    T2R11
    T2R3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001025149.1 → NP_001020320.1  taste receptor type 2 member 3

      See identical proteins and their annotated locations for NP_001020320.1

      Status: PROVISIONAL

      Source sequence(s)
      AY362733
      UniProtKB/Swiss-Prot
      Q67ET7
      UniProtKB/TrEMBL
      A6IEX7
      Related
      ENSRNOP00000059873.1, ENSRNOT00000046917.5
      Conserved Domains (1) summary
      cd15020
      Location:7 → 296
      7tm_TAS2R3; mammalian taste receptor 2, subtype 3, member of the seven-transmembrane G protein-coupled receptor superfamily

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086022.1 Reference GRCr8

      Range
      70242964..70256215
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006236362.5 → XP_006236424.1  taste receptor type 2 member 3 isoform X1

      See identical proteins and their annotated locations for XP_006236424.1

      UniProtKB/Swiss-Prot
      Q67ET7
      UniProtKB/TrEMBL
      A6IEX7
      Conserved Domains (1) summary
      cd15020
      Location:7 → 296
      7tm_TAS2R3; mammalian taste receptor 2, subtype 3, member of the seven-transmembrane G protein-coupled receptor superfamily
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q67ET7.1 GenPept UniProtKB/Swiss-Prot:Q67ET7

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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