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    Mas1l MAS1 proto-oncogene like, G protein-coupled receptor [ Rattus norvegicus (Norway rat) ]

    Gene ID: 404641, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Mas1lprovided by RGD
    Official Full Name
    MAS1 proto-oncogene like, G protein-coupled receptorprovided by RGD
    Primary source
    RGD:738049
    See related
    EnsemblRapid:ENSRNOG00000083618 AllianceGenome:RGD:738049
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Mgrb; Mrgprh; MrgHGPR90
    Summary
    Predicted to enable angiotensin receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in cytosol and nucleoplasm. Predicted to be active in plasma membrane. Orthologous to human MAS1L (MAS1 proto-oncogene like, G protein-coupled receptor). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Muscle (RPKM 5.0), Heart (RPKM 3.7) and 7 other tissues See more
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    Genomic context

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    See Mas1l in Genome Data Viewer
    Location:
    1q11
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (50416178..50427730, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (47871592..47879942, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (48068389..48206902, complement)

    Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene mitochondrial ribosomal protein L18 Neighboring gene PARN like ribonuclease domain containing exonuclease 1 Neighboring gene MAS1 proto-oncogene, G protein-coupled receptor Neighboring gene uncharacterized LOC120099123

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Atypical expansion in mice of the sensory neuron-specific Mrg G protein-coupled receptor family. Zylka MJ, et al. Proc Natl Acad Sci U S A, 2003 Aug 19. PMID 12909716, Free PMC Article
    2. Comparative genomic analysis of eutherian Mas-related G protein-coupled receptor genes. Premzl M. Gene, 2014 Apr 25. PMID 24583173
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables G protein-coupled receptor activity TAS
    Traceable Author Statement
    more info
    		 PubMed 
    enables angiotensin receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in G protein-coupled receptor signaling pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in angiotensin-activated signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in plasma membrane ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    mas-related G-protein coupled receptor member H
    Names
    MAS-related G-protein coupled receptor, member H
    MAS-related GPR, member H
    MAS-related gene H
    Mas-related G protein-coupled receptor b

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001002281.1 → NP_001002281.1  mas-related G-protein coupled receptor member H

      See identical proteins and their annotated locations for NP_001002281.1

      Status: PROVISIONAL

      Source sequence(s)
      AF518249
      UniProtKB/Swiss-Prot
      Q7TN38
      UniProtKB/TrEMBL
      W8W3K0
      Related
      ENSRNOP00000101421.1, ENSRNOT00000133314.1
      Conserved Domains (1) summary
      cd15110
      Location:36 → 306
      7tmA_MrgprH; mas-related G protein-coupled receptor subtype H, member of the class A family of seven-transmembrane G protein-coupled receptors

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086019.1 Reference GRCr8

      Range
      50416178..50427730 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006227882.5 → XP_006227944.1  mas-related G-protein coupled receptor member H isoform X1

      See identical proteins and their annotated locations for XP_006227944.1

      UniProtKB/Swiss-Prot
      Q7TN38
      UniProtKB/TrEMBL
      W8W3K0
      Related
      ENSRNOP00000101054.1, ENSRNOT00000167238.1
      Conserved Domains (1) summary
      cd15110
      Location:36 → 306
      7tmA_MrgprH; mas-related G protein-coupled receptor subtype H, member of the class A family of seven-transmembrane G protein-coupled receptors
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q7TN38.1 GenPept UniProtKB/Swiss-Prot:Q7TN38

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Chemical Information
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