Pcdhb2 protocadherin beta 2 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Pcdhb2provided by RGD
Official Full Name: protocadherin beta 2provided by RGD
Primary source: RGD:1563132
See related: EnsemblRapid:ENSRNOG00000039476 AllianceGenome:RGD:1563132
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: RGD1563132
Summary: Predicted to enable calcium ion binding activity. Predicted to be involved in cell adhesion. Predicted to be active in plasma membrane. Orthologous to human PCDHB2 (protocadherin beta 2). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: human mouse all
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Genomic context

Location:: 18p11

Exon count:: 1

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	18	NC_086036.1 (29280004..29282790)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	18	NC_051353.1 (29005996..29008782)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	18	NC_005117.4 (30375798..30378194)

Chromosome 18 - NC_086036.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables calcium ion binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in cell adhesion	IBA Inferred from Biological aspect of Ancestor more info
involved_in homophilic cell adhesion via plasma membrane adhesion molecules	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in plasma membrane	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: protocadherin beta-2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001109123.2 → NP_001102593.2 protocadherin beta-2 precursor

Status: VALIDATED

Source sequence(s)

JAXUCZ010000018

UniProtKB/TrEMBL

A6J358, F1M7D0

Related

ENSRNOP00000057239.3, ENSRNOT00000060497.4

Conserved Domains (3) summary

cd11304
Location:243 → 339

Cadherin_repeat; Cadherin tandem repeat domain

pfam08266
Location:27 → 108

Cadherin_2; Cadherin-like

pfam16492
Location:683 → 765

Cadherin_C_2; Cadherin cytoplasmic C-terminal