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    Tmem104 transmembrane protein 104 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 303670, updated on 4-Jan-2025

    Summary

    Official Symbol
    Tmem104provided by RGD
    Official Full Name
    transmembrane protein 104provided by RGD
    Primary source
    RGD:1307953
    See related
    EnsemblRapid:ENSRNOG00000025669 AllianceGenome:RGD:1307953
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1307953
    Summary
    Predicted to be located in membrane. Orthologous to human TMEM104 (transmembrane protein 104). [provided by Alliance of Genome Resources, Jan 2025]
    Expression
    Biased expression in Kidney (RPKM 33.6), Adrenal (RPKM 26.7) and 9 other tissues See more
    Orthologs
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    Genomic context

    See Tmem104 in Genome Data Viewer
    Location:
    10q32.1
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 10 NC_086028.1 (100926219..100984870)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 10 NC_051345.1 (100427244..100485890)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (103737162..103795751)

    Chromosome 10 - NC_086028.1Genomic Context describing neighboring genes Neighboring gene RAB37, member RAS oncogene family Neighboring gene Cd300 molecule-like family member F Neighboring gene NHERF family PDZ scaffold protein 1 Neighboring gene N-acetyltransferase 9 Neighboring gene uncharacterized LOC134480900 Neighboring gene glutamate ionotropic receptor NMDA type subunit 2C Neighboring gene ferredoxin reductase

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001191655.1NP_001178584.1  transmembrane protein 104

      See identical proteins and their annotated locations for NP_001178584.1

      Status: PROVISIONAL

      Source sequence(s)
      JAXUCZ010000010
      UniProtKB/TrEMBL
      A0A8I6A1J9, D3ZU40
      Related
      ENSRNOP00000051915.2, ENSRNOT00000055037.5
      Conserved Domains (2) summary
      COG0814
      Location:21487
      SdaC; Amino acid permease [Amino acid transport and metabolism]
      cl00456
      Location:25441
      SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086028.1 Reference GRCr8

      Range
      100926219..100984870
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039086190.2XP_038942118.1  transmembrane protein 104 isoform X3

      Conserved Domains (1) summary
      cl00456
      Location:2259
      SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain
    2. XM_039086189.1XP_038942117.1  transmembrane protein 104 isoform X2

      UniProtKB/TrEMBL
      A0A8I6A1J9
      Conserved Domains (1) summary
      cl00456
      Location:25440
      SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain
    3. XM_039086191.2XP_038942119.1  transmembrane protein 104 isoform X4

      UniProtKB/TrEMBL
      A6HKL1
      Conserved Domains (1) summary
      cl00456
      Location:2259
      SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain
    4. XM_006247715.5XP_006247777.1  transmembrane protein 104 isoform X1

      See identical proteins and their annotated locations for XP_006247777.1

      UniProtKB/TrEMBL
      A0A8I6A1J9, D3ZU40
      Conserved Domains (2) summary
      COG0814
      Location:21487
      SdaC; Amino acid permease [Amino acid transport and metabolism]
      cl00456
      Location:25441
      SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain
    5. XM_039086192.1XP_038942120.1  transmembrane protein 104 isoform X5

      Conserved Domains (1) summary
      cl00456
      Location:18213
      SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain