U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    Taar8c trace amine-associated receptor 8C [ Rattus norvegicus (Norway rat) ]

    Gene ID: 319105, updated on 9-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    Taar8cprovided by RGD
    Official Full Name
    trace amine-associated receptor 8Cprovided by RGD
    Primary source
    RGD:631390
    See related
    AllianceGenome:RGD:631390
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Ta10
    Summary
    Enables trace-amine receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be active in plasma membrane. Orthologous to human TAAR8 (trace amine associated receptor 8). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Testes (RPKM 5.1), Thymus (RPKM 2.0) and 2 other tissues See more
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See Taar8c in Genome Data Viewer
    Location:
    1p12
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (23107601..23110321)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (21289843..21290877)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (22332047..22333121)

    Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene ribosomal protein S29, pseudogene 21 Neighboring gene trace amine-associated receptor 9 Neighboring gene trace amine-associated receptor 8B Neighboring gene trace amine associated receptor 8A

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Expression

    Go to the top of the page Help
    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Agonists for 13 trace amine-associated receptors provide insight into the molecular basis of odor selectivity. Ferrero DM, et al. ACS Chem Biol, 2012 Jul 20. PMID 22545963, Free PMC Article
    2. Trace amines: identification of a family of mammalian G protein-coupled receptors. Borowsky B, et al. Proc Natl Acad Sci U S A, 2001 Jul 31. PMID 11459929, Free PMC Article
    3. Trace amine-associated receptors form structurally and functionally distinct subfamilies of novel G protein-coupled receptors. Lindemann L, et al. Genomics, 2005 Mar. PMID 15718104
    4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables trace-amine receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables trace-amine receptor activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables trace-amine receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables trace-amine receptor activity ISO
    Inferred from Sequence Orthology
    more info
    		  
    Process Evidence Code Pubs
    involved_in G protein-coupled receptor signaling pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in G protein-coupled receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    trace amine-associated receptor 8c
    Names
    taR-10
    taR-8c
    trace amine receptor 10
    trace amine receptor 8c

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_175600.2 → NP_783190.2  trace amine-associated receptor 8c

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000001
      UniProtKB/Swiss-Prot
      Q923Y0
      UniProtKB/TrEMBL
      A0A0G2JSV7, A0A9K3Y7Q7, Q5QD18

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086019.1 Reference GRCr8

      Range
      23107601..23110321
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063265664.1 → XP_063121734.1  trace amine-associated receptor 8c isoform X1

      UniProtKB/Swiss-Prot
      Q923Y0
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q923Y0.1 GenPept UniProtKB/Swiss-Prot:Q923Y0

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials
    Tools
    Miscellaneous