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    Cldn9 claudin 9 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 287099, updated on 9-Dec-2024

    Summary

    Official Symbol
    Cldn9provided by RGD
    Official Full Name
    claudin 9provided by RGD
    Primary source
    RGD:1308999
    See related
    EnsemblRapid:ENSRNOG00000089717 AllianceGenome:RGD:1308999
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable virus receptor activity. Predicted to be involved in bicellular tight junction assembly and cell adhesion. Predicted to act upstream of or within tight junction organization. Predicted to be located in cell junction and intracellular membrane-bounded organelle. Predicted to be active in bicellular tight junction and plasma membrane. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 116. Orthologous to human CLDN9 (claudin 9). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See Cldn9 in Genome Data Viewer
    Location:
    10q12
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 10 NC_086028.1 (13218728..13220159, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 10 NC_051345.1 (12714137..12715568, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (13003010..13004441, complement)

    Chromosome 10 - NC_086028.1Genomic Context describing neighboring genes Neighboring gene TNF receptor superfamily member 12A Neighboring gene claudin 6 Neighboring gene vegetative cell wall protein gp1-like Neighboring gene glycine rich extracellular protein 1 Neighboring gene protein kinase, membrane associated tyrosine/threonine 1

    Genomic regions, transcripts, and products

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables virus receptor activity ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within cell-cell junction organization ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within tight junction organization ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in bicellular tight junction ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cell junction ISO
    Inferred from Sequence Orthology
    more info
     
    located_in intracellular membrane-bounded organelle ISO
    Inferred from Sequence Orthology
    more info
     
    located_in plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001011889.2NP_001011889.1  claudin-9

      See identical proteins and their annotated locations for NP_001011889.1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000010
      UniProtKB/TrEMBL
      Q5PPJ3
      Related
      ENSRNOP00000110097.1, ENSRNOT00000165237.1
      Conserved Domains (1) summary
      cl21598
      Location:4163
      PMP22_Claudin; PMP-22/EMP/MP20/Claudin family

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086028.1 Reference GRCr8

      Range
      13218728..13220159 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)