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    Zmat2 zinc finger, matrin type 2 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 679898, updated on 9-Dec-2024

    Summary

    Official Symbol
    Zmat2provided by RGD
    Official Full Name
    zinc finger, matrin type 2provided by RGD
    Primary source
    RGD:1583592
    See related
    EnsemblRapid:ENSRNOG00000072190 AllianceGenome:RGD:1583592
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable ATP binding activity; nucleic acid binding activity; and zinc ion binding activity. Predicted to be involved in mRNA splicing, via spliceosome. Predicted to be located in nucleus. Predicted to be part of U2-type precatalytic spliceosome and U4/U6 x U5 tri-snRNP complex. Orthologous to human ZMAT2 (zinc finger matrin-type 2). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Brain (RPKM 202.5), Muscle (RPKM 186.2) and 9 other tissues See more
    Orthologs
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    Genomic context

    See Zmat2 in Genome Data Viewer
    Location:
    18p11
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 18 NC_086036.1 (28683617..28688252)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 18 NC_051353.1 (28409606..28414241)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 18 NC_005117.4 (29639991..29644626)

    Chromosome 18 - NC_086036.1Genomic Context describing neighboring genes Neighboring gene small nucleolar RNA SNORA72 Neighboring gene histidyl-tRNA synthetase 1 Neighboring gene histidyl-tRNA synthetase 2, mitochondrial Neighboring gene protocadherin alpha 4 Neighboring gene zinc finger protein 260, pseudogene 1 Neighboring gene U2 spliceosomal RNA

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in mRNA splicing, via spliceosome ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    part_of U2-type precatalytic spliceosome ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    zinc finger matrin-type protein 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001135582.1NP_001129054.1  zinc finger matrin-type protein 2

      See identical proteins and their annotated locations for NP_001129054.1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000018
      UniProtKB/TrEMBL
      A6J341, D4AD01
      Related
      ENSRNOP00000090091.2, ENSRNOT00000104252.2
      Conserved Domains (2) summary
      smart00451
      Location:77108
      ZnF_U1; U1-like zinc finger
      pfam08648
      Location:178196
      DUF1777; Protein of unknown function (DUF1777)

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086036.1 Reference GRCr8

      Range
      28683617..28688252
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)