U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    Sult4a1 sulfotransferase family 4A, member 1 [ Mus musculus (house mouse) ]

    Gene ID: 29859, updated on 9-Dec-2024

    Summary

    Official Symbol
    Sult4a1provided by MGI
    Official Full Name
    sulfotransferase family 4A, member 1provided by MGI
    Primary source
    MGI:MGI:1888971
    See related
    Ensembl:ENSMUSG00000018865 AllianceGenome:MGI:1888971
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    NST; ST4A1; BR-STL; Sultx3; mBR-STL; BR-STL-1; 2400007A17Rik
    Summary
    Enables sulfotransferase activity. Acts upstream of or within sulfur compound metabolic process. Located in cytosol and mitochondrion. Is expressed in embryo. Orthologous to human SULT4A1 (sulfotransferase family 4A member 1). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in cortex adult (RPKM 100.2), cerebellum adult (RPKM 83.3) and 4 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Sult4a1 in Genome Data Viewer
    Location:
    15 E2; 15 39.73 cM
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 15 NC_000081.7 (83960298..83989955, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 15 NC_000081.6 (84076097..84105754, complement)

    Chromosome 15 - NC_000081.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 41372 Neighboring gene STARR-seq mESC enhancer starr_39344 Neighboring gene EF-hand calcium binding domain 6 Neighboring gene ribosomal protein L31, pseudogene 22 Neighboring gene predicted gene, 46526 Neighboring gene patatin-like phospholipase domain containing 5 Neighboring gene predicted gene, 33432

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables identical protein binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables identical protein binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables sulfotransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables sulfotransferase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in dendrite arborization IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in dendrite arborization ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in steroid metabolic process IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in sulfation IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within sulfur compound metabolic process IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in cytoplasm TAS
    Traceable Author Statement
    more info
    PubMed 
    located_in cytosol IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in mitochondrion IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    sulfotransferase 4A1
    Names
    brain sulfotransferase-like protein
    nervous system sulfotransferase
    sulfotransferase-related protein
    NP_001343444.1
    NP_038901.3

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001356515.1NP_001343444.1  sulfotransferase 4A1 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AL603867
      Consensus CDS
      CCDS88819.1
      UniProtKB/TrEMBL
      Q8BQV8
      Related
      ENSMUSP00000155695.2, ENSMUST00000229826.2
      Conserved Domains (1) summary
      pfam00685
      Location:45230
      Sulfotransfer_1; Sulfotransferase domain
    2. NM_013873.3NP_038901.3  sulfotransferase 4A1 isoform 1

      See identical proteins and their annotated locations for NP_038901.3

      Status: VALIDATED

      Source sequence(s)
      BC054757
      Consensus CDS
      CCDS27708.1
      UniProtKB/Swiss-Prot
      O88872, P63046, Q3TXY5, Q91XS5, Q9CWY7, Q9DC97
      UniProtKB/TrEMBL
      Q8BQV8
      Related
      ENSMUSP00000080973.6, ENSMUST00000082365.6
      Conserved Domains (1) summary
      pfam00685
      Location:45277
      Sulfotransfer_1; Sulfotransferase domain

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000081.7 Reference GRCm39 C57BL/6J

      Range
      83960298..83989955 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)