Links from GEO Profiles

Showing Current items.

Rims2 regulating synaptic membrane exocytosis 2 [ Mus musculus (house mouse) ]

Gene ID: 116838, updated on 9-Dec-2024

Summary

Go to the top of the page Help

Official Symbol: Rims2provided by MGI
Official Full Name: regulating synaptic membrane exocytosis 2provided by MGI
Primary source: MGI:MGI:2152972
See related: Ensembl:ENSMUSG00000037386 AllianceGenome:MGI:2152972
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: RIM2; Serg2; Rab3ip2; Syt3-rs; Rim2(+4A); mKIAA0751; Rim2(+40A); Rim2(+44A); 2810036I15Rik
Summary: Enables protein-macromolecule adaptor activity and transmembrane transporter binding activity. A structural constituent of presynaptic active zone. Involved in several processes, including neurotransmitter secretion; regulation of calcium-dependent activation of synaptic vesicle fusion; and regulation of nervous system process. Acts upstream of or within several processes, including adenylate cyclase-modulating G protein-coupled receptor signaling pathway; regulation of exocytosis; and signal release. Located in inhibitory synapse. Is active in GABA-ergic synapse and glutamatergic synapse. Is expressed in testis. Orthologous to human RIMS2 (regulating synaptic membrane exocytosis 2). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Biased expression in cerebellum adult (RPKM 7.7), cortex adult (RPKM 5.5) and 7 other tissues See more
Orthologs: human all
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help

See Rims2 in Genome Data Viewer

Location:: 15 B3.1; 15 15.45 cM

Exon count:: 38

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	15	NC_000081.7 (39061681..39547768)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	15	NC_000081.6 (39198286..39684372)

Chromosome 15 - NC_000081.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Gene knockout of RNA binding motif 5 in the brain alters RIMS2 protein homeostasis in the cerebellum and Hippocampus and exacerbates behavioral deficits after a TBI in mice.
Title: Gene knockout of RNA binding motif 5 in the brain alters RIMS2 protein homeostasis in the cerebellum and Hippocampus and exacerbates behavioral deficits after a TBI in mice.
N6-methyladenosine-modified circRIMS2 mediates synaptic and memory impairments by activating GluN2B ubiquitination in Alzheimer's disease.
Title: N6-methyladenosine-modified circRIMS2 mediates synaptic and memory impairments by activating GluN2B ubiquitination in Alzheimer's disease.
Here, the authors identify an essential role for the active zone protein RIM in stimulated somatodendritic dopamine release in the midbrain. In mice in which RIMs are selectively removed from dopamine neurons, action potentials failed to evoke significant somatodendritic release detected via D2 receptor-mediated currents.
Title: RIM is essential for stimulated but not spontaneous somatodendritic dopamine release in the midbrain.
RBPs perform unexpectedly broad roles at the active zone that together with those of RIMs are essential for all active zone functions.
Title: How to Make an Active Zone: Unexpected Universal Functional Redundancy between RIMs and RIM-BPs.
Electrophysiological characterization of VDCC currents revealed that the suppressive effect of RIM2alpha on voltage-dependent inactivation (VDI) was stronger than that of RIM1alpha for the CaV2.1 variant containing the region encoded by exons 44 and 47.
Title: C-terminal splice variants of P/Q-type Ca(2+) channel Ca(V)2.1 α(1) subunits are differentially regulated by Rab3-interacting molecule proteins.
The function of RIM1/2 at rod ribbons is to enhance Cav1.4 channel activity, possibly through direct or indirect modulation of the channel.
Title: RIM1/2-Mediated Facilitation of Cav1.4 Channel Opening Is Required for Ca2+-Stimulated Release in Mouse Rod Photoreceptors.
RIM2alpha and RIM2beta promote a large complement of synaptic CaV1.3 Ca(2+) channels at inner hair cell presynaptic active zones and are required for normal hearing.
Title: Rab3-interacting molecules 2α and 2β promote the abundance of voltage-gated CaV1.3 Ca2+ channels at hair cell active zones.
Experiments with single Rim 1/2 gene inactivation at the large calyx of Held synapse show largely overlapping roles of the two major Rim genes in vesicle priming/docking
Title: RIM1 and RIM2 redundantly determine Ca2+ channel density and readily releasable pool size at a large hindbrain synapse.
Rim2alpha is involved in Zona Pellucida dependent signaling.
Title: RIM2α is a molecular scaffold for Zona pellucida-induced acrosome reaction.
Data suggest that RIM1/2 proteins co-ordinately regulate key functions for fast transmitter release, enabling a high presynaptic Ca(2)+ channel density and vesicle docking at the active zone.
Title: RIM determines Ca²+ channel density and vesicle docking at the presynaptic active zone.

Submit: New GeneRIF Correction See all GeneRIFs (14)

Variation

Go to the top of the page Help

Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Endonuclease-mediated (1)
Targeted (6) 1 citation

Interactions

Go to the top of the page Help

Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

Go to the top of the page Help

Markers

AW048769 (e-PCR)
- UniSTS:165922

fc03a12.x1 (e-PCR)
- UniSTS:192096

Rims2 (e-PCR), detects polymorphism
- UniSTS:508539

Syt3-rs (e-PCR), detects polymorphism
- UniSTS:144532

10.MMHAP64FRD7.seq (e-PCR)
- UniSTS:123039

29.MMHAP24FLB5.seq (e-PCR)
- UniSTS:123855

Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables metal ion binding	IEA Inferred from Electronic Annotation more info
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed
enables protein domain specific binding	ISO Inferred from Sequence Orthology more info
enables protein-containing complex binding	ISO Inferred from Sequence Orthology more info
enables protein-macromolecule adaptor activity	IDA Inferred from Direct Assay more info	PubMed
enables protein-macromolecule adaptor activity	ISO Inferred from Sequence Orthology more info	PubMed
enables small GTPase binding	IEA Inferred from Electronic Annotation more info
enables structural constituent of presynaptic active zone	IBA Inferred from Biological aspect of Ancestor more info
enables structural constituent of presynaptic active zone	IDA Inferred from Direct Assay more info	PubMed
enables structural constituent of presynaptic active zone	IEP Inferred from Expression Pattern more info	PubMed
enables structural constituent of presynaptic active zone	IMP Inferred from Mutant Phenotype more info	PubMed
enables transmembrane transporter binding	IDA Inferred from Direct Assay more info	PubMed

Process	Evidence Code	Pubs
acts_upstream_of_or_within adenylate cyclase-modulating G protein-coupled receptor signaling pathway	IDA Inferred from Direct Assay more info	PubMed
acts_upstream_of_or_within calcium ion-regulated exocytosis of neurotransmitter	IGI Inferred from Genetic Interaction more info	PubMed
acts_upstream_of_or_within calcium-ion regulated exocytosis	IDA Inferred from Direct Assay more info	PubMed
involved_in cell differentiation	IEA Inferred from Electronic Annotation more info
involved_in establishment of localization in cell	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within insulin secretion	IDA Inferred from Direct Assay more info	PubMed
involved_in insulin secretion	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in intracellular protein transport	IEA Inferred from Electronic Annotation more info
involved_in maintenance of presynaptic active zone structure	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within neurotransmitter secretion	IGI Inferred from Genetic Interaction more info	PubMed
involved_in positive regulation of dendrite extension	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of excitatory postsynaptic potential	IGI Inferred from Genetic Interaction more info	PubMed
involved_in positive regulation of gene expression	IGI Inferred from Genetic Interaction more info	PubMed
involved_in positive regulation of inhibitory postsynaptic potential	IGI Inferred from Genetic Interaction more info	PubMed
involved_in regulation of calcium-dependent activation of synaptic vesicle fusion	IDA Inferred from Direct Assay more info	PubMed
involved_in regulation of calcium-dependent activation of synaptic vesicle fusion	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within regulation of exocytosis	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within regulation of membrane potential	IDA Inferred from Direct Assay more info	PubMed
involved_in regulation of synaptic vesicle exocytosis	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within regulation of synaptic vesicle exocytosis	ISO Inferred from Sequence Orthology more info
involved_in spontaneous neurotransmitter secretion	IGI Inferred from Genetic Interaction more info	PubMed
involved_in synaptic vesicle docking	IBA Inferred from Biological aspect of Ancestor more info
involved_in synaptic vesicle docking	IDA Inferred from Direct Assay more info	PubMed
involved_in synaptic vesicle docking	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in synaptic vesicle priming	IBA Inferred from Biological aspect of Ancestor more info
involved_in synaptic vesicle priming	IDA Inferred from Direct Assay more info	PubMed
involved_in synaptic vesicle priming	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
is_active_in GABA-ergic synapse	IDA Inferred from Direct Assay more info	PubMed
is_active_in GABA-ergic synapse	IMP Inferred from Mutant Phenotype more info	PubMed
is_active_in glutamatergic synapse	IDA Inferred from Direct Assay more info	PubMed
is_active_in glutamatergic synapse	IMP Inferred from Mutant Phenotype more info	PubMed
located_in inhibitory synapse	IMP Inferred from Mutant Phenotype more info	PubMed
located_in membrane	IEA Inferred from Electronic Annotation more info
located_in neuron projection	IEA Inferred from Electronic Annotation more info
is_active_in photoreceptor ribbon synapse	ISO Inferred from Sequence Orthology more info
located_in presynapse	IEA Inferred from Electronic Annotation more info
is_active_in presynaptic active zone cytoplasmic component	IBA Inferred from Biological aspect of Ancestor more info
is_active_in presynaptic active zone cytoplasmic component	ISO Inferred from Sequence Orthology more info
is_active_in presynaptic membrane	IBA Inferred from Biological aspect of Ancestor more info
part_of protein-containing complex	ISO Inferred from Sequence Orthology more info

General protein information

Go to the top of the page Help

Preferred Names: regulating synaptic membrane exocytosis protein 2

Names: RIM 2; Rab3 interacting protein 1; Rab3 interacting protein 2; rab-3-interacting protein 2; rab3-interacting protein 2; synaptic exocytosis regulator 2; synaptotagmin 3, related sequence

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001256382.1 → NP_001243311.1 regulating synaptic membrane exocytosis protein 2 isoform a

See identical proteins and their annotated locations for NP_001243311.1

Status: VALIDATED

Description

Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (a).

Source sequence(s)

AC101886, AC101935, AC114537

Consensus CDS

CCDS56982.1

UniProtKB/TrEMBL

D9HP81, Q6ZQ55

Related

ENSMUSP00000048719.10, ENSMUST00000042917.10

Conserved Domains (5) summary

cd04028
Location:1403 → 1548

C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins

cd04031
Location:774 → 900

C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins

PHA02666
Location:1001 → 1101

PHA02666; hypothetical protein; Provisional

cd00992
Location:640 → 721

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

cl22851
Location:30 → 154

PHD_SF; PHD finger superfamily
NM_001256383.1 → NP_001243312.1 regulating synaptic membrane exocytosis protein 2 isoform b

See identical proteins and their annotated locations for NP_001243312.1

Status: VALIDATED

Description

Transcript Variant: This variant (2) lacks an in-frame exon in the coding region, compared to variant 1. It encodes isoform b which is shorter than isoform a.

Source sequence(s)

AC101886, AC101935, AC114537

Consensus CDS

CCDS88755.1

UniProtKB/TrEMBL

Q0VF51, Q6ZQ55

Related

ENSMUSP00000154153.2, ENSMUST00000227243.2

Conserved Domains (4) summary

cd04028
Location:1381 → 1526

C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins

cd04031
Location:774 → 900

C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins

cd00992
Location:640 → 721

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

cl22851
Location:30 → 154

PHD_SF; PHD finger superfamily
NM_001256384.1 → NP_001243313.1 regulating synaptic membrane exocytosis protein 2 isoform d

See identical proteins and their annotated locations for NP_001243313.1

Status: VALIDATED

Description

Transcript Variant: This variant (4) lacks most of the 5' exons, includes an alternate 5' terminal exon and maintains the reading frame, compared to variant 1. It encodes isoform d which is shorter than isoform a.

Source sequence(s)

AC114537, AK032619

Consensus CDS

CCDS88756.1

UniProtKB/Swiss-Prot

Q9EQZ7

Related

ENSMUSP00000153868.2, ENSMUST00000226410.2

Conserved Domains (1) summary

cd04028
Location:116 → 261

C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins
NM_053271.2 → NP_444501.1 regulating synaptic membrane exocytosis protein 2 isoform c

See identical proteins and their annotated locations for NP_444501.1

Status: VALIDATED

Description

Transcript Variant: This variant (3) has multiple differences in the coding region but maintains the reading frame, compared to variant 1. It encodes isoform c which is shorter than isoform a.

Source sequence(s)

AB021131, AK032619, BY242489

Consensus CDS

CCDS37067.1

UniProtKB/Swiss-Prot

Q8C433, Q8CCK2, Q9EQZ7

Related

ENSMUSP00000080711.6, ENSMUST00000082054.12

Conserved Domains (4) summary

cd04028
Location:1361 → 1506

C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins

cd04031
Location:814 → 940

C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins

cd00992
Location:680 → 761

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

cl22851
Location:30 → 194

PHD_SF; PHD finger superfamily

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

NC_000081.7 Reference GRCm39 C57BL/6J

Range

39061681..39547768

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_017316372.2 → XP_017171861.1 regulating synaptic membrane exocytosis protein 2 isoform X4

Conserved Domains (5) summary

cd04028
Location:1453 → 1598

C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins

cd04031
Location:780 → 903

C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins

PHA02666
Location:1013 → 1114

PHA02666; hypothetical protein; Provisional

cd00992
Location:627 → 708

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

cl22851
Location:118 → 168

PHD_SF; PHD finger superfamily
XM_036159081.1 → XP_036014974.1 regulating synaptic membrane exocytosis protein 2 isoform X12

UniProtKB/TrEMBL

Q6ZQ55

Conserved Domains (5) summary

cd04028
Location:1417 → 1562

C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins

cd04031
Location:780 → 903

C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins

PHA02666
Location:1004 → 1104

PHA02666; hypothetical protein; Provisional

cd00992
Location:627 → 708

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

cl22851
Location:118 → 168

PHD_SF; PHD finger superfamily
XM_036159079.1 → XP_036014972.1 regulating synaptic membrane exocytosis protein 2 isoform X5

UniProtKB/TrEMBL

Q6ZQ55

Conserved Domains (5) summary

cd04028
Location:1437 → 1582

C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins

cd04031
Location:761 → 887

C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins

PHA02666
Location:997 → 1098

PHA02666; hypothetical protein; Provisional

cd00992
Location:627 → 708

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

cl22851
Location:118 → 168

PHD_SF; PHD finger superfamily
XM_017316375.2 → XP_017171864.1 regulating synaptic membrane exocytosis protein 2 isoform X9

UniProtKB/TrEMBL

Q6ZQ55

Conserved Domains (5) summary

cd04028
Location:1428 → 1573

C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins

cd04031
Location:761 → 887

C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins

PHA02666
Location:988 → 1089

PHA02666; hypothetical protein; Provisional

cd00992
Location:627 → 708

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

cl22851
Location:118 → 168

PHD_SF; PHD finger superfamily
XM_036159082.1 → XP_036014975.1 regulating synaptic membrane exocytosis protein 2 isoform X15

UniProtKB/TrEMBL

Q6ZQ55

Conserved Domains (4) summary

cd04028
Location:1405 → 1550

C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins

cd04031
Location:761 → 887

C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins

cd00992
Location:627 → 708

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

cl22851
Location:118 → 168

PHD_SF; PHD finger superfamily
XM_017316373.2 → XP_017171862.1 regulating synaptic membrane exocytosis protein 2 isoform X6

UniProtKB/TrEMBL

Q6ZQ55

Conserved Domains (5) summary

cd04028
Location:1433 → 1578

C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins

cd04031
Location:760 → 883

C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins

PHA02666
Location:993 → 1094

PHA02666; hypothetical protein; Provisional

cd00992
Location:607 → 688

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

cl22851
Location:118 → 168

PHD_SF; PHD finger superfamily
XM_017316374.2 → XP_017171863.1 regulating synaptic membrane exocytosis protein 2 isoform X7

UniProtKB/TrEMBL

Q6ZQ55

Conserved Domains (5) summary

cd04028
Location:1432 → 1577

C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins

cd04031
Location:760 → 883

C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins

PHA02666
Location:993 → 1093

PHA02666; hypothetical protein; Provisional

cd00992
Location:607 → 688

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

cl22851
Location:118 → 168

PHD_SF; PHD finger superfamily
XM_036159080.1 → XP_036014973.1 regulating synaptic membrane exocytosis protein 2 isoform X10

UniProtKB/TrEMBL

Q6ZQ55

Conserved Domains (5) summary

cd04028
Location:1423 → 1568

C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins

cd04031
Location:760 → 883

C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins

PHA02666
Location:984 → 1084

PHA02666; hypothetical protein; Provisional

cd00992
Location:607 → 688

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

cl22851
Location:118 → 168

PHD_SF; PHD finger superfamily
XM_030248287.1 → XP_030104147.1 regulating synaptic membrane exocytosis protein 2 isoform X13

UniProtKB/TrEMBL

Q6ZQ55

Conserved Domains (5) summary

cd04028
Location:1417 → 1562

C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins

cd04031
Location:741 → 867

C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins

PHA02666
Location:977 → 1078

PHA02666; hypothetical protein; Provisional

cd00992
Location:607 → 688

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

cl22851
Location:118 → 168

PHD_SF; PHD finger superfamily
XM_017316380.2 → XP_017171869.1 regulating synaptic membrane exocytosis protein 2 isoform X14

UniProtKB/TrEMBL

Q6ZQ55

Conserved Domains (5) summary

cd04028
Location:1407 → 1552

C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins

cd04031
Location:741 → 867

C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins

PHA02666
Location:968 → 1068

PHA02666; hypothetical protein; Provisional

cd00992
Location:607 → 688

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

cl22851
Location:118 → 168

PHD_SF; PHD finger superfamily
XM_017316370.2 → XP_017171859.1 regulating synaptic membrane exocytosis protein 2 isoform X1

Conserved Domains (5) summary

cd04028
Location:1480 → 1625

C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins

cd04031
Location:807 → 930

C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins

PHA02666
Location:1040 → 1141

PHA02666; hypothetical protein; Provisional

cd00992
Location:654 → 735

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

cl22851
Location:118 → 168

PHD_SF; PHD finger superfamily
XM_017316371.2 → XP_017171860.1 regulating synaptic membrane exocytosis protein 2 isoform X3

Conserved Domains (5) summary

cd04028
Location:1464 → 1609

C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins

cd04031
Location:788 → 914

C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins

PHA02666
Location:1024 → 1125

PHA02666; hypothetical protein; Provisional

cd00992
Location:654 → 735

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

cl22851
Location:118 → 168

PHD_SF; PHD finger superfamily
XM_030248286.1 → XP_030104146.1 regulating synaptic membrane exocytosis protein 2 isoform X8

UniProtKB/TrEMBL

Q6ZQ55

Conserved Domains (5) summary

cd04028
Location:1429 → 1574

C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins

cd04031
Location:756 → 879

C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins

PHA02666
Location:989 → 1090

PHA02666; hypothetical protein; Provisional

cd00992
Location:603 → 684

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

cl28890
Location:118 → 162

FYVE_like_SF; FYVE domain like superfamily
XM_017316376.2 → XP_017171865.1 regulating synaptic membrane exocytosis protein 2 isoform X11

UniProtKB/TrEMBL

Q6ZQ55

Conserved Domains (5) summary

cd04028
Location:1419 → 1564

C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins

cd04031
Location:756 → 879

C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins

PHA02666
Location:980 → 1080

PHA02666; hypothetical protein; Provisional

cd00992
Location:603 → 684

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

cl28890
Location:118 → 162

FYVE_like_SF; FYVE domain like superfamily
XM_030248285.1 → XP_030104145.1 regulating synaptic membrane exocytosis protein 2 isoform X2

Conserved Domains (5) summary

cd04028
Location:1476 → 1621

C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins

cd04031
Location:803 → 926

C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins

PHA02666
Location:1036 → 1137

PHA02666; hypothetical protein; Provisional

cd00992
Location:650 → 731

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

cl28890
Location:118 → 162

FYVE_like_SF; FYVE domain like superfamily
XM_017316385.3 → XP_017171874.1 regulating synaptic membrane exocytosis protein 2 isoform X19

UniProtKB/TrEMBL

Q6ZQ55

Conserved Domains (4) summary

cd04028
Location:1247 → 1392

C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins

cd04031
Location:574 → 697

C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins

PHA02666
Location:807 → 908

PHA02666; hypothetical protein; Provisional

cd00992
Location:421 → 502

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
XM_017316401.3 → XP_017171890.1 regulating synaptic membrane exocytosis protein 2 isoform X33

UniProtKB/TrEMBL

Q6ZQ55

Conserved Domains (4) summary

cd04028
Location:1028 → 1173

C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins

cd04031
Location:574 → 697

C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins

PHA02666
Location:798 → 898

PHA02666; hypothetical protein; Provisional

cd00992
Location:421 → 502

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
XM_017316403.3 → XP_017171892.1 regulating synaptic membrane exocytosis protein 2 isoform X35

UniProtKB/TrEMBL

Q6ZQ55

Conserved Domains (4) summary

cd04028
Location:1021 → 1166

C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins

cd04031
Location:555 → 681

C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins

PHA02666
Location:791 → 891

PHA02666; hypothetical protein; Provisional

cd00992
Location:421 → 502

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
XM_036159089.1 → XP_036014982.1 regulating synaptic membrane exocytosis protein 2 isoform X40

UniProtKB/TrEMBL

Q6ZQ55

Conserved Domains (3) summary

cd04028
Location:999 → 1144

C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins

cd04031
Location:555 → 681

C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins

cd00992
Location:421 → 502

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
XM_017316405.3 → XP_017171894.1 regulating synaptic membrane exocytosis protein 2 isoform X37

UniProtKB/TrEMBL

Q6ZQ55

Conserved Domains (4) summary

cd04028
Location:1012 → 1157

C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins

cd04031
Location:555 → 681

C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins

PHA02666
Location:782 → 882

PHA02666; hypothetical protein; Provisional

cd00992
Location:421 → 502

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
XM_017316387.3 → XP_017171876.1 regulating synaptic membrane exocytosis protein 2 isoform X20

UniProtKB/TrEMBL

Q6ZQ55

Conserved Domains (4) summary

cd04028
Location:1227 → 1372

C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins

cd04031
Location:554 → 677

C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins

PHA02666
Location:787 → 888

PHA02666; hypothetical protein; Provisional

cd00992
Location:401 → 482

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
XM_030248298.2 → XP_030104158.1 regulating synaptic membrane exocytosis protein 2 isoform X43

UniProtKB/TrEMBL

Q6ZQ55

Conserved Domains (4) summary

cd04028
Location:987 → 1132

C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins

cd04031
Location:554 → 677

C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins

PHA03307
Location:680 → 922

PHA03307; transcriptional regulator ICP4; Provisional

cd00992
Location:401 → 482

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
XM_036159088.1 → XP_036014981.1 regulating synaptic membrane exocytosis protein 2 isoform X38

UniProtKB/TrEMBL

Q6ZQ55

Conserved Domains (4) summary

cd04028
Location:1008 → 1153

C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins

cd04031
Location:554 → 677

C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins

PHA02666
Location:778 → 878

PHA02666; hypothetical protein; Provisional

cd00992
Location:401 → 482

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
XM_017316410.3 → XP_017171899.1 regulating synaptic membrane exocytosis protein 2 isoform X44

UniProtKB/TrEMBL

Q6ZQ55

Conserved Domains (4) summary

cd04028
Location:986 → 1131

C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins

cd04031
Location:554 → 677

C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins

PHA03307
Location:680 → 921

PHA03307; transcriptional regulator ICP4; Provisional

cd00992
Location:401 → 482

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
XM_030248300.2 → XP_030104160.1 regulating synaptic membrane exocytosis protein 2 isoform X48

UniProtKB/TrEMBL

Q6ZQ55

Conserved Domains (3) summary

cd04028
Location:926 → 1071

C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins

cd04031
Location:554 → 677

C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins

cd00992
Location:401 → 482

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
XM_017316389.3 → XP_017171878.1 regulating synaptic membrane exocytosis protein 2 isoform X21

UniProtKB/TrEMBL

Q6ZQ55

Conserved Domains (4) summary

cd04028
Location:1211 → 1356

C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins

cd04031
Location:535 → 661

C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins

PHA02666
Location:771 → 872

PHA02666; hypothetical protein; Provisional

cd00992
Location:401 → 482

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
XM_030248292.2 → XP_030104152.1 regulating synaptic membrane exocytosis protein 2 isoform X22

UniProtKB/TrEMBL

Q6ZQ55

Conserved Domains (4) summary

cd04028
Location:1210 → 1355

C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins

cd04031
Location:535 → 661

C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins

PHA02666
Location:771 → 871

PHA02666; hypothetical protein; Provisional

cd00992
Location:401 → 482

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
XM_017316407.3 → XP_017171896.1 regulating synaptic membrane exocytosis protein 2 isoform X39

UniProtKB/TrEMBL

Q6ZQ55

Conserved Domains (4) summary

cd04028
Location:1001 → 1146

C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins

cd04031
Location:535 → 661

C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins

PHA02666
Location:771 → 871

PHA02666; hypothetical protein; Provisional

cd00992
Location:401 → 482

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
XM_036159085.1 → XP_036014978.1 regulating synaptic membrane exocytosis protein 2 isoform X25

UniProtKB/TrEMBL

Q6ZQ55

Conserved Domains (3) summary

cd04028
Location:1188 → 1333

C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins

cd04031
Location:535 → 661

C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins

cd00992
Location:401 → 482

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
XM_036159090.1 → XP_036014983.1 regulating synaptic membrane exocytosis protein 2 isoform X45

UniProtKB/TrEMBL

Q6ZQ55

Conserved Domains (3) summary

cd04028
Location:979 → 1124

C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins

cd04031
Location:535 → 661

C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins

cd00992
Location:401 → 482

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
XM_030248293.2 → XP_030104153.1 regulating synaptic membrane exocytosis protein 2 isoform X23

UniProtKB/TrEMBL

Q6ZQ55

Conserved Domains (4) summary

cd04028
Location:1202 → 1347

C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins

cd04031
Location:535 → 661

C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins

PHA02666
Location:762 → 863

PHA02666; hypothetical protein; Provisional

cd00992
Location:401 → 482

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
XM_017316409.3 → XP_017171898.1 regulating synaptic membrane exocytosis protein 2 isoform X41

UniProtKB/TrEMBL

Q6ZQ55

Conserved Domains (5) summary

TIGR00934
Location:659 → 934

2a38euk; potassium uptake protein, Trk family

cd04028
Location:993 → 1138

C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins

cd04031
Location:535 → 661

C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins

PHA02666
Location:762 → 863

PHA02666; hypothetical protein; Provisional

cd00992
Location:401 → 482

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
XM_030248296.2 → XP_030104156.1 regulating synaptic membrane exocytosis protein 2 isoform X28

UniProtKB/TrEMBL

Q6ZQ55

Conserved Domains (4) summary

cd04028
Location:1154 → 1299

C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins

cd04031
Location:535 → 661

C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins

PHA03307
Location:664 → 896

PHA03307; transcriptional regulator ICP4; Provisional

cd00992
Location:401 → 482

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
XM_030248299.2 → XP_030104159.1 regulating synaptic membrane exocytosis protein 2 isoform X46

UniProtKB/TrEMBL

Q6ZQ55

Conserved Domains (4) summary

cd04028
Location:971 → 1116

C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins

cd04031
Location:535 → 661

C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins

PHA03307
Location:664 → 906

PHA03307; transcriptional regulator ICP4; Provisional

cd00992
Location:401 → 482

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
XM_030248301.2 → XP_030104161.1 regulating synaptic membrane exocytosis protein 2 isoform X49

UniProtKB/TrEMBL

Q6ZQ55

Conserved Domains (3) summary

cd04028
Location:911 → 1056

C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins

cd04031
Location:535 → 661

C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins

cd00992
Location:401 → 482

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
XM_030248294.2 → XP_030104154.1 regulating synaptic membrane exocytosis protein 2 isoform X24

UniProtKB/TrEMBL

Q6ZQ55

Conserved Domains (4) summary

cd04028
Location:1190 → 1335

C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins

cd04031
Location:535 → 661

C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins

PHA03307
Location:730 → 935

PHA03307; transcriptional regulator ICP4; Provisional

cd00992
Location:401 → 482

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
XM_017316397.3 → XP_017171886.1 regulating synaptic membrane exocytosis protein 2 isoform X27

UniProtKB/TrEMBL

Q6ZQ55

Conserved Domains (4) summary

cd04028
Location:1164 → 1309

C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins

cd04031
Location:535 → 661

C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins

PHA03307
Location:730 → 935

PHA03307; transcriptional regulator ICP4; Provisional

cd00992
Location:401 → 482

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
XM_006520343.5 → XP_006520406.1 regulating synaptic membrane exocytosis protein 2 isoform X42

UniProtKB/TrEMBL

Q6ZQ55

Conserved Domains (4) summary

cd04028
Location:992 → 1137

C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins

cd04031
Location:535 → 661

C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins

PHA02666
Location:762 → 862

PHA02666; hypothetical protein; Provisional

cd00992
Location:401 → 482

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
XM_030248295.2 → XP_030104155.1 regulating synaptic membrane exocytosis protein 2 isoform X26

UniProtKB/TrEMBL

Q6ZQ55

Related

ENSMUSP00000154531.2, ENSMUST00000227381.2

Conserved Domains (3) summary

cd04028
Location:1179 → 1324

C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins

cd04031
Location:535 → 661

C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins

cd00992
Location:401 → 482

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
XM_036159086.1 → XP_036014979.1 regulating synaptic membrane exocytosis protein 2 isoform X29

UniProtKB/TrEMBL

Q6ZQ55

Conserved Domains (4) summary

cd04028
Location:1142 → 1287

C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins

cd04031
Location:535 → 661

C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins

PHA03307
Location:664 → 904

PHA03307; transcriptional regulator ICP4; Provisional

cd00992
Location:401 → 482

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
XM_017316412.3 → XP_017171901.1 regulating synaptic membrane exocytosis protein 2 isoform X47

UniProtKB/TrEMBL

Q6ZQ55

Conserved Domains (4) summary

cd04028
Location:970 → 1115

C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins

cd04031
Location:535 → 661

C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins

PHA03307
Location:664 → 905

PHA03307; transcriptional regulator ICP4; Provisional

cd00992
Location:401 → 482

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
XM_036159083.1 → XP_036014976.1 regulating synaptic membrane exocytosis protein 2 isoform X16

UniProtKB/TrEMBL

Q6ZQ55

Conserved Domains (4) summary

cd04028
Location:1274 → 1419

C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins

cd04031
Location:601 → 724

C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins

PHA02666
Location:834 → 935

PHA02666; hypothetical protein; Provisional

cd00992
Location:448 → 529

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
XM_017316399.3 → XP_017171888.1 regulating synaptic membrane exocytosis protein 2 isoform X30

UniProtKB/TrEMBL

Q6ZQ55

Conserved Domains (4) summary

cd04028
Location:1064 → 1209

C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins

cd04031
Location:601 → 724

C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins

PHA02666
Location:834 → 934

PHA02666; hypothetical protein; Provisional

cd00992
Location:448 → 529

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
XM_036159084.1 → XP_036014977.1 regulating synaptic membrane exocytosis protein 2 isoform X17

UniProtKB/TrEMBL

Q6ZQ55

Conserved Domains (4) summary

cd04028
Location:1258 → 1403

C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins

cd04031
Location:582 → 708

C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins

PHA02666
Location:818 → 919

PHA02666; hypothetical protein; Provisional

cd00992
Location:448 → 529

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
XM_017316400.3 → XP_017171889.1 regulating synaptic membrane exocytosis protein 2 isoform X31

UniProtKB/TrEMBL

Q6ZQ55

Conserved Domains (5) summary

cd04028
Location:1048 → 1193

C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins

cd04031
Location:582 → 708

C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins

PHA02666
Location:818 → 918

PHA02666; hypothetical protein; Provisional

PHA03307
Location:786 → 997

PHA03307; transcriptional regulator ICP4; Provisional

cd00992
Location:448 → 529

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
XM_036159087.1 → XP_036014980.1 regulating synaptic membrane exocytosis protein 2 isoform X34

UniProtKB/TrEMBL

Q6ZQ55

Conserved Domains (3) summary

cd04028
Location:1026 → 1171

C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins

cd04031
Location:582 → 708

C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins

cd00992
Location:448 → 529

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
XM_030248297.2 → XP_030104157.1 regulating synaptic membrane exocytosis protein 2 isoform X32

UniProtKB/TrEMBL

Q6ZQ55

Conserved Domains (5) summary

TIGR00934
Location:706 → 981

2a38euk; potassium uptake protein, Trk family

cd04028
Location:1040 → 1185

C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins

cd04031
Location:582 → 708

C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins

PHA02666
Location:809 → 910

PHA02666; hypothetical protein; Provisional

cd00992
Location:448 → 529

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
XM_017316404.3 → XP_017171893.1 regulating synaptic membrane exocytosis protein 2 isoform X36

UniProtKB/TrEMBL

Q6ZQ55

Conserved Domains (4) summary

cd04028
Location:1018 → 1163

C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins

cd04031
Location:582 → 708

C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins

PHA03307
Location:711 → 953

PHA03307; transcriptional regulator ICP4; Provisional

cd00992
Location:448 → 529

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
XM_017316384.3 → XP_017171873.1 regulating synaptic membrane exocytosis protein 2 isoform X18

UniProtKB/TrEMBL

Q6ZQ55

Conserved Domains (4) summary

cd04028
Location:1248 → 1393

C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins

cd04031
Location:582 → 708

C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins

PHA02666
Location:809 → 909

PHA02666; hypothetical protein; Provisional

cd00992
Location:448 → 529

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...