Psmd8 proteasome 26S subunit, non-ATPase 8 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Psmd8provided by RGD
Official Full Name: proteasome 26S subunit, non-ATPase 8provided by RGD
Primary source: RGD:1309842
See related: EnsemblRapid:ENSRNOG00000037580 AllianceGenome:RGD:1309842
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary: Predicted to be involved in proteasome-mediated ubiquitin-dependent protein catabolic process. Predicted to be part of proteasome regulatory particle, lid subcomplex. Predicted to be active in nucleus. Orthologous to human PSMD8 (proteasome 26S subunit, non-ATPase 8). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Biased expression in Testes (RPKM 407.7), Liver (RPKM 349.7) and 9 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 1q21

Exon count:: 7

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	1	NC_086019.1 (93601857..93608689, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	1	NC_051336.1 (84474377..84481209, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	1	NC_005100.4 (88116811..88123643, complement)

Chromosome 1 - NC_086019.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

RH124225 (e-PCR)
- UniSTS:161047

RH131189 (e-PCR)
- UniSTS:214472

Gene Ontology Provided by RGD

Process	Evidence Code	Pubs
involved_in proteasome-mediated ubiquitin-dependent protein catabolic process	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info
part_of proteasome accessory complex	ISO Inferred from Sequence Orthology more info
part_of proteasome complex	ISO Inferred from Sequence Orthology more info
part_of proteasome regulatory particle, lid subcomplex	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: 26S proteasome non-ATPase regulatory subunit 8

Names: proteasome (prosome, macropain) 26S subunit, non-ATPase, 8

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001100831.1 → NP_001094301.1 26S proteasome non-ATPase regulatory subunit 8

Status: VALIDATED

Source sequence(s)

BC105894, CD371338, CK844749

UniProtKB/TrEMBL

A6J9P2, F1LMQ3

Related

ENSRNOP00000027937.5, ENSRNOT00000027937.7

Conserved Domains (1) summary

pfam10075
Location:204 → 318

CSN8_PSD8_EIF3K; CSN8/PSMD8/EIF3K family