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    Cyp2c54 cytochrome P450, family 2, subfamily c, polypeptide 54 [ Mus musculus (house mouse) ]

    Gene ID: 404195, updated on 27-Nov-2024

    Summary

    Official Symbol
    Cyp2c54provided by MGI
    Official Full Name
    cytochrome P450, family 2, subfamily c, polypeptide 54provided by MGI
    Primary source
    MGI:MGI:3642960
    See related
    Ensembl:ENSMUSG00000067225 AllianceGenome:MGI:3642960
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    EG404195
    Summary
    Enables arachidonate epoxygenase activity and linoleic acid epoxygenase activity. Acts upstream of or within arachidonate metabolic process and linoleic acid metabolic process. Predicted to be located in endoplasmic reticulum membrane. Predicted to be active in cytoplasm and intracellular membrane-bounded organelle. [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Restricted expression toward liver adult (RPKM 103.0) See more
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    Genomic context

    See Cyp2c54 in Genome Data Viewer
    Location:
    19 C3; 19 34.24 cM
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 19 NC_000085.7 (40026383..40062289, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 19 NC_000085.6 (40037939..40073845, complement)

    Chromosome 19 - NC_000085.7Genomic Context describing neighboring genes Neighboring gene cytochrome P450, family 2, subfamily c, polypeptide 71, pseudogene Neighboring gene STARR-seq mESC enhancer starr_46124 Neighboring gene STARR-seq mESC enhancer starr_46125 Neighboring gene cytochrome P450, family 2. subfamily c, polypeptide 37 Neighboring gene cytochrome P450, family 2, subfamily c, polypeptide 50 Neighboring gene STARR-seq mESC enhancer starr_46126 Neighboring gene cytochrome P450, family 2, subfamily c, polypeptide 70

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Process Evidence Code Pubs
    acts_upstream_of_or_within arachidonate metabolic process IDA
    Inferred from Direct Assay
    more info
    PubMed 
    acts_upstream_of_or_within linoleic acid metabolic process IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in organic acid metabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in xenobiotic metabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in endoplasmic reticulum membrane IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in intracellular membrane-bounded organelle IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    cytochrome P450 2C54
    Names
    CYPIIC54
    NP_996260.1
    XP_006527235.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_206537.2NP_996260.1  cytochrome P450 2C54

      See identical proteins and their annotated locations for NP_996260.1

      Status: VALIDATED

      Source sequence(s)
      AI046359, AI047349, AI181879, BF659738
      Consensus CDS
      CCDS29800.1
      UniProtKB/Swiss-Prot
      Q6XVG2
      UniProtKB/TrEMBL
      Q9DBD9
      Related
      ENSMUSP00000048284.4, ENSMUST00000048959.5
      Conserved Domains (1) summary
      pfam00067
      Location:30487
      p450; Cytochrome P450

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000085.7 Reference GRCm39 C57BL/6J

      Range
      40026383..40062289 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006527172.2XP_006527235.1  cytochrome P450 2C54 isoform X1

      UniProtKB/TrEMBL
      Q9DBD9
      Conserved Domains (1) summary
      pfam00067
      Location:30428
      p450; Cytochrome P450