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    Ppil6 peptidylprolyl isomerase (cyclophilin)-like 6 [ Mus musculus (house mouse) ]

    Gene ID: 73075, updated on 3-Dec-2024

    Summary

    Official Symbol
    Ppil6provided by MGI
    Official Full Name
    peptidylprolyl isomerase (cyclophilin)-like 6provided by MGI
    Primary source
    MGI:MGI:1920325
    See related
    Ensembl:ENSMUSG00000078451 AllianceGenome:MGI:1920325
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    2900084F20Rik
    Summary
    Predicted to enable peptidyl-prolyl cis-trans isomerase activity. Predicted to be involved in protein peptidyl-prolyl isomerization. Predicted to be active in cytoplasm. Orthologous to human PPIL6 (peptidylprolyl isomerase like 6). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Broad expression in testis adult (RPKM 8.2), bladder adult (RPKM 5.6) and 15 other tissues See more
    Orthologs
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    Genomic context

    See Ppil6 in Genome Data Viewer
    Location:
    10 B1- B2; 10 22.43 cM
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 10 NC_000076.7 (41366414..41390286)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 10 NC_000076.6 (41490371..41514295)

    Chromosome 10 - NC_000076.7Genomic Context describing neighboring genes Neighboring gene CapStarr-seq enhancer MGSCv37_chr10:41197812-41197921 Neighboring gene predicted gene, 51797 Neighboring gene microtubule associated monooxygenase, calponin and LIM domain containing 1 Neighboring gene sphingomyelin phosphodiesterase 2, neutral Neighboring gene STARR-positive B cell enhancer ABC_E2932 Neighboring gene STARR-positive B cell enhancer ABC_E5127 Neighboring gene CD164 antigen Neighboring gene CapStarr-seq enhancer MGSCv37_chr10:41272644-41272850 Neighboring gene coiled-coil domain containing 162 Neighboring gene predicted gene 17196

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 

    General protein information

    Preferred Names
    probable inactive peptidyl-prolyl cis-trans isomerase-like 6
    Names
    PPIase
    cyclophilin-like protein PPIL6
    peptidyl-prolyl cis-trans isomerase-like 6
    problable inactive peptidyl-prolyl cis-trans isomerase-like 6
    rotamase PPIL6
    NP_001394931.1
    NP_001394932.1
    NP_001394933.1
    NP_001394934.1
    NP_001394935.1
    NP_001394936.1
    NP_082706.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001408002.1NP_001394931.1  probable inactive peptidyl-prolyl cis-trans isomerase-like 6 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC153360
    2. NM_001408003.1NP_001394932.1  probable inactive peptidyl-prolyl cis-trans isomerase-like 6 isoform 3

      Status: VALIDATED

      Source sequence(s)
      AC132290, AC153360
    3. NM_001408004.1NP_001394933.1  probable inactive peptidyl-prolyl cis-trans isomerase-like 6 isoform 4

      Status: VALIDATED

      Source sequence(s)
      AC132290, AC153360
    4. NM_001408005.1NP_001394934.1  probable inactive peptidyl-prolyl cis-trans isomerase-like 6 isoform 5

      Status: VALIDATED

      Source sequence(s)
      AC153360
    5. NM_001408006.1NP_001394935.1  probable inactive peptidyl-prolyl cis-trans isomerase-like 6 isoform 6

      Status: VALIDATED

      Source sequence(s)
      AC132290, AC153360
      UniProtKB/TrEMBL
      A0A1L1SS02
      Related
      ENSMUSP00000149689.2, ENSMUST00000214145.2
    6. NM_001408007.1NP_001394936.1  probable inactive peptidyl-prolyl cis-trans isomerase-like 6 isoform 6

      Status: VALIDATED

      Source sequence(s)
      AC132290, AC153360
      UniProtKB/TrEMBL
      A0A1L1SS02
    7. NM_028430.2NP_082706.1  probable inactive peptidyl-prolyl cis-trans isomerase-like 6 isoform 1

      See identical proteins and their annotated locations for NP_082706.1

      Status: VALIDATED

      Source sequence(s)
      AC132290, AC153360
      Consensus CDS
      CCDS48548.1
      UniProtKB/Swiss-Prot
      B2RWF7, Q9D6D8
      Related
      ENSMUSP00000101146.4, ENSMUST00000105507.5
      Conserved Domains (1) summary
      cl00197
      Location:146309
      cyclophilin; cyclophilin: cyclophilin-type peptidylprolyl cis- trans isomerases. This family contains eukaryotic, bacterial and archeal proteins which exhibit a peptidylprolyl cis- trans isomerases activity (PPIase, Rotamase) and in addition bind the ...

    RNA

    1. NR_176439.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC132290, AC153360
    2. NR_176440.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC132290, AC153360
    3. NR_176441.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC132290, AC153360

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000076.7 Reference GRCm39 C57BL/6J

      Range
      41366414..41390286
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    RNA

    1. XR_871442.4 RNA Sequence

    2. XR_380080.5 RNA Sequence