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    Nif3l1 Ngg1 interacting factor 3-like 1 (S. pombe) [ Mus musculus (house mouse) ]

    Gene ID: 65102, updated on 9-Dec-2024

    Summary

    Official Symbol
    Nif3l1provided by MGI
    Official Full Name
    Ngg1 interacting factor 3-like 1 (S. pombe)provided by MGI
    Primary source
    MGI:MGI:1929485
    See related
    Ensembl:ENSMUSG00000026036 AllianceGenome:MGI:1929485
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    1110030G24Rik
    Summary
    This gene is a member of the NGG1-interacting factor 3-like superfamily of transcriptional regulators and is ubiquitously expressed throughout embryonic development. The encoded protein interacts with a component of the constitutive photomorphogenesis 9 signalosome, and functions as a transcriptional corepressor of genes involved in neuronal differentiation. This gene is highly conserved from bacteria to human. [provided by RefSeq, Sep 2016]
    Expression
    Ubiquitous expression in CNS E11.5 (RPKM 13.3), CNS E14 (RPKM 12.7) and 28 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Nif3l1 in Genome Data Viewer
    Location:
    1 C1.3; 1 29.1 cM
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 1 NC_000067.7 (58484310..58501435)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 1 NC_000067.6 (58445151..58462276)

    Chromosome 1 - NC_000067.7Genomic Context describing neighboring genes Neighboring gene CapStarr-seq enhancer MGSCv37_chr1:58450605-58450792 Neighboring gene predicted gene, 53481 Neighboring gene basic leucine zipper and W2 domains 1 Neighboring gene STARR-seq mESC enhancer starr_01013 Neighboring gene CapStarr-seq enhancer MGSCv37_chr1:58480276-58480459 Neighboring gene STARR-positive B cell enhancer ABC_E5756 Neighboring gene CDC-like kinase 1 Neighboring gene CapStarr-seq enhancer MGSCv37_chr1:58501960-58502147 Neighboring gene CapStarr-seq enhancer MGSCv37_chr1:58502340-58502523 Neighboring gene peptidylprolyl isomerase (cyclophilin)-like 3 Neighboring gene predicted gene, 23966 Neighboring gene origin recognition complex, subunit 2 Neighboring gene STARR-seq mESC enhancer starr_01014 Neighboring gene STARR-positive B cell enhancer ABC_E3277 Neighboring gene STARR-seq mESC enhancer starr_01015 Neighboring gene predicted gene 15834 Neighboring gene hyccin PI4KA lipid kinase complex subunit 2

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Clone Names

    • MGC107114

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables RNA polymerase II-specific DNA-binding transcription factor binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables RNA polymerase II-specific DNA-binding transcription factor binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables identical protein binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables identical protein binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in mitochondrion HDA PubMed 
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    NIF3-like protein 1
    Names
    GTP cyclohydrolase I
    Ngg1 interacting factor 3 homolog-like 1
    putative GTP cyclohydrolase 1 type 2 Nif3l1
    NP_075364.2
    XP_006496249.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_022988.3NP_075364.2  NIF3-like protein 1

      See identical proteins and their annotated locations for NP_075364.2

      Status: REVIEWED

      Source sequence(s)
      AC118698, AK158616, BC065163
      Consensus CDS
      CCDS14973.1
      UniProtKB/Swiss-Prot
      Q6P1B7, Q9D098, Q9EQ80
      UniProtKB/TrEMBL
      Q3V2R8
      Related
      ENSMUSP00000084799.7, ENSMUST00000087521.13
      Conserved Domains (1) summary
      pfam01784
      Location:32353
      NIF3; NIF3 (NGG1p interacting factor 3)

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000067.7 Reference GRCm39 C57BL/6J

      Range
      58484310..58501435
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006496186.2XP_006496249.1  NIF3-like protein 1 isoform X1

      See identical proteins and their annotated locations for XP_006496249.1

      UniProtKB/Swiss-Prot
      Q6P1B7, Q9D098, Q9EQ80
      UniProtKB/TrEMBL
      Q3V2R8
      Conserved Domains (1) summary
      pfam01784
      Location:32353
      NIF3; NIF3 (NGG1p interacting factor 3)