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    Nfatc2ip nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 2 interacting protein [ Mus musculus (house mouse) ]

    Gene ID: 18020, updated on 9-Dec-2024

    Summary

    Official Symbol
    Nfatc2ipprovided by MGI
    Official Full Name
    nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 2 interacting proteinprovided by MGI
    Primary source
    MGI:MGI:1329015
    See related
    Ensembl:ENSMUSG00000030722 AllianceGenome:MGI:1329015
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    NIP45; D7Ertd304e
    Summary
    Acts upstream of or within positive regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Is expressed in early embryo; eye; genitourinary system; and limb. Orthologous to human NFATC2IP (nuclear factor of activated T cells 2 interacting protein). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Ubiquitous expression in testis adult (RPKM 15.5), thymus adult (RPKM 7.6) and 28 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Nfatc2ip in Genome Data Viewer
    Location:
    7 F3; 7 69.01 cM
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (125982025..125995909, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (126382853..126396796, complement)

    Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene CapStarr-seq enhancer MGSCv37_chr7:133513013-133513200 Neighboring gene microRNA 7058 Neighboring gene linker for activation of T cells Neighboring gene CapStarr-seq enhancer MGSCv37_chr7:133521004-133521187 Neighboring gene SPNS lysolipid transporter 1, lysophospholipid Neighboring gene STARR-seq mESC enhancer starr_20144 Neighboring gene CapStarr-seq enhancer MGSCv37_chr7:133540343-133540526 Neighboring gene STARR-positive B cell enhancer ABC_E8208 Neighboring gene STARR-positive B cell enhancer ABC_E9706 Neighboring gene CD19 antigen Neighboring gene STARR-positive B cell enhancer ABC_E9707 Neighboring gene rabaptin, RAB GTPase binding effector protein 2 Neighboring gene ATPase, Ca++ transporting, cardiac muscle, fast twitch 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (3) 
    • Targeted (1)  1 citation

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General protein information

    Preferred Names
    NFATC2-interacting protein
    Names
    45 kDa NF-AT-interacting protein
    45 kDa NFAT-interacting protein
    nuclear factor of activated T-cells, cytoplasmic 2-interacting protein

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001412712.1NP_001399641.1  NFATC2-interacting protein isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC125322
    2. NM_001412713.1NP_001399642.1  NFATC2-interacting protein isoform 3

      Status: VALIDATED

      Source sequence(s)
      AC125322
    3. NM_010900.4NP_035030.2  NFATC2-interacting protein isoform 1

      See identical proteins and their annotated locations for NP_035030.2

      Status: VALIDATED

      Source sequence(s)
      AC125322
      Consensus CDS
      CCDS21827.1
      UniProtKB/Swiss-Prot
      O09130, Q8CDG2, Q9CVY5
      Related
      ENSMUSP00000075094.5, ENSMUST00000075671.5
      Conserved Domains (2) summary
      smart00213
      Location:258327
      UBQ; Ubiquitin homologues
      cl00155
      Location:341410
      UBQ; Ubiquitin-like proteins

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000073.7 Reference GRCm39 C57BL/6J

      Range
      125982025..125995909 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)