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    Ptgfrn prostaglandin F2 receptor negative regulator [ Mus musculus (house mouse) ]

    Gene ID: 19221, updated on 9-Dec-2024

    Summary

    Official Symbol
    Ptgfrnprovided by MGI
    Official Full Name
    prostaglandin F2 receptor negative regulatorprovided by MGI
    Primary source
    MGI:MGI:1277114
    See related
    Ensembl:ENSMUSG00000027864 AllianceGenome:MGI:1277114
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    FPRP; EWI-F; CD9P-1; Trim45; 4833445A08Rik
    Summary
    Involved in myoblast fusion involved in skeletal muscle regeneration. Acts upstream of or within lipid droplet organization. Predicted to be located in Golgi apparatus and endoplasmic reticulum membrane. Predicted to be active in membrane. Is expressed in several structures, including central nervous system; glans of male genital tubercle; palatal shelf; skeleton; and submandibular gland primordium. Orthologous to human PTGFRN (prostaglandin F2 receptor inhibitor). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Broad expression in lung adult (RPKM 30.6), bladder adult (RPKM 17.8) and 21 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Ptgfrn in Genome Data Viewer
    Location:
    3 F2.2; 3 43.93 cM
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 3 NC_000069.7 (100947546..101018061, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 3 NC_000069.6 (101040230..101110745, complement)

    Chromosome 3 - NC_000069.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E2678 Neighboring gene transcription termination factor, RNA polymerase II Neighboring gene CD101 antigen Neighboring gene STARR-seq mESC enhancer starr_08505 Neighboring gene STARR-seq mESC enhancer starr_08514 Neighboring gene STARR-seq mESC enhancer starr_08516 Neighboring gene STARR-seq mESC enhancer starr_08517 Neighboring gene STARR-seq mESC enhancer starr_08518 Neighboring gene nuclear import 7 pseudogene Neighboring gene tumor protein, translationally-controlled, pseudogene 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (3) 
    • Gene trapped (1) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in Golgi apparatus IEA
    Inferred from Electronic Annotation
    more info
     
    located_in endoplasmic reticulum membrane IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    prostaglandin F2 receptor negative regulator
    Names
    CD9 partner 1
    glu-Trp-Ile EWI motif-containing protein F
    prostaglandin F2-alpha receptor regulatory protein
    prostaglandin F2-alpha receptor-associated protein

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_011197.3NP_035327.2  prostaglandin F2 receptor negative regulator precursor

      See identical proteins and their annotated locations for NP_035327.2

      Status: VALIDATED

      Source sequence(s)
      AL645930, AL669872
      Consensus CDS
      CCDS17680.1
      UniProtKB/Swiss-Prot
      Q5SRA8, Q9WV91
      UniProtKB/TrEMBL
      Q69ZJ6
      Related
      ENSMUSP00000099755.4, ENSMUST00000102694.4
      Conserved Domains (3) summary
      smart00406
      Location:39121
      IGv; Immunoglobulin V-Type
      smart00410
      Location:29140
      IG_like; Immunoglobulin like
      cl11960
      Location:283375
      Ig; Immunoglobulin domain

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000069.7 Reference GRCm39 C57BL/6J

      Range
      100947546..101018061 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017319503.2XP_017174992.1  prostaglandin F2 receptor negative regulator isoform X1

      UniProtKB/TrEMBL
      Q69ZJ6
      Conserved Domains (2) summary
      smart00406
      Location:36118
      IGv; Immunoglobulin V-Type
      smart00409
      Location:281372
      IG; Immunoglobulin
    2. XM_006501147.4XP_006501210.1  prostaglandin F2 receptor negative regulator isoform X2

      See identical proteins and their annotated locations for XP_006501210.1

      UniProtKB/TrEMBL
      Q69ZJ6
      Conserved Domains (2) summary
      smart00406
      Location:27109
      IGv; Immunoglobulin V-Type
      smart00409
      Location:272363
      IG; Immunoglobulin