U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    Zfp819 zinc finger protein 819 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 308561, updated on 9-Dec-2024

    Summary

    Official Symbol
    Zfp819provided by RGD
    Official Full Name
    zinc finger protein 819provided by RGD
    Primary source
    RGD:1309564
    See related
    EnsemblRapid:ENSRNOG00000022701 EnsemblRapid:ENSRNOG00000030160 AllianceGenome:RGD:1309564
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1309564
    Summary
    Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in membrane. Predicted to be active in nucleus. Orthologous to human ZNF175 (zinc finger protein 175). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Testes (RPKM 40.5), Kidney (RPKM 21.6) and 9 other tissues See more
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Zfp819 in Genome Data Viewer
    Location:
    1q22
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (103163570..103222203)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (94027347..94048767)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (99521177..99539232)

    Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene zinc finger protein 658 Neighboring gene zinc finger protein 719 Neighboring gene uncharacterized LOC120099801 Neighboring gene CEA cell adhesion molecule 18 Neighboring gene sialic acid binding Ig-like lectin 8 Neighboring gene cytosolic thiouridylase subunit 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables RNA polymerase II transcription regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001014017.2NP_001014039.1  zinc finger protein 175

      See identical proteins and their annotated locations for NP_001014039.1

      Status: PROVISIONAL

      Source sequence(s)
      BC087070
      UniProtKB/TrEMBL
      A0A9K3Y6N2, F7EPA9, Q5PQR1
      Related
      ENSRNOP00000024662.6, ENSRNOT00000024662.8
      Conserved Domains (5) summary
      smart00349
      Location:2781
      KRAB; krueppel associated box
      COG5048
      Location:346538
      COG5048; FOG: Zn-finger [General function prediction only]
      COG5189
      Location:499582
      SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
      sd00017
      Location:449469
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam13465
      Location:573598
      zf-H2C2_2; Zinc-finger double domain

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086019.1 Reference GRCr8

      Range
      103163570..103222203
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006229046.5XP_006229108.1  zinc finger protein 175 isoform X1

      See identical proteins and their annotated locations for XP_006229108.1

      UniProtKB/TrEMBL
      A0A9K3Y6N2, F7EPA9, Q5PQR1
      Conserved Domains (5) summary
      smart00349
      Location:2781
      KRAB; krueppel associated box
      COG5048
      Location:346538
      COG5048; FOG: Zn-finger [General function prediction only]
      COG5189
      Location:499582
      SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
      sd00017
      Location:449469
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam13465
      Location:573598
      zf-H2C2_2; Zinc-finger double domain
    2. XM_039111789.2XP_038967717.1  zinc finger protein 175 isoform X1

      UniProtKB/TrEMBL
      A0A9K3Y6N2, F7EPA9, Q5PQR1
      Conserved Domains (5) summary
      smart00349
      Location:2781
      KRAB; krueppel associated box
      COG5048
      Location:346538
      COG5048; FOG: Zn-finger [General function prediction only]
      COG5189
      Location:499582
      SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
      sd00017
      Location:449469
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam13465
      Location:573598
      zf-H2C2_2; Zinc-finger double domain
    3. XM_063261749.1XP_063117819.1  zinc finger protein 175 isoform X2

    4. XM_017589129.3XP_017444618.1  zinc finger protein 175 isoform X1

      UniProtKB/TrEMBL
      A0A9K3Y6N2, F7EPA9, Q5PQR1
      Conserved Domains (5) summary
      smart00349
      Location:2781
      KRAB; krueppel associated box
      COG5048
      Location:346538
      COG5048; FOG: Zn-finger [General function prediction only]
      COG5189
      Location:499582
      SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
      sd00017
      Location:449469
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam13465
      Location:573598
      zf-H2C2_2; Zinc-finger double domain
    5. XM_063261741.1XP_063117811.1  zinc finger protein 175 isoform X1

      UniProtKB/TrEMBL
      A0A9K3Y6N2, F7EPA9, Q5PQR1
    6. XM_063261747.1XP_063117817.1  zinc finger protein 175 isoform X1

      UniProtKB/TrEMBL
      A0A9K3Y6N2, F7EPA9, Q5PQR1
    7. XM_063261731.1XP_063117801.1  zinc finger protein 175 isoform X1

      UniProtKB/TrEMBL
      A0A9K3Y6N2, F7EPA9, Q5PQR1
    8. XM_006229047.5XP_006229109.1  zinc finger protein 175 isoform X1

      See identical proteins and their annotated locations for XP_006229109.1

      UniProtKB/TrEMBL
      A0A9K3Y6N2, F7EPA9, Q5PQR1
      Conserved Domains (5) summary
      smart00349
      Location:2781
      KRAB; krueppel associated box
      COG5048
      Location:346538
      COG5048; FOG: Zn-finger [General function prediction only]
      COG5189
      Location:499582
      SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
      sd00017
      Location:449469
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam13465
      Location:573598
      zf-H2C2_2; Zinc-finger double domain
    9. XM_063261753.1XP_063117823.1  zinc finger protein 175 isoform X3

      UniProtKB/TrEMBL
      D3ZXU3
      Related
      ENSRNOP00000103128.1, ENSRNOT00000157655.1

    RNA

    1. XR_010052073.1 RNA Sequence