Snapc3 small nuclear RNA activating complex, polypeptide 3 [Rattus norvegicus (Norway rat)] - Gene

Summary

Symbol: Snapc3provided by RGD
Full Name: small nuclear RNA activating complex, polypeptide 3provided by RGD
Primary source: RGD:1305172
See related: EnsemblRapid:ENSRNOG00000010825 AllianceGenome:RGD:1305172
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary: Predicted to enable RNA polymerase III type 3 promoter sequence-specific DNA binding activity and bent DNA binding activity. Predicted to contribute to RNA polymerase II cis-regulatory region sequence-specific DNA binding activity and core promoter sequence-specific DNA binding activity. Predicted to be involved in snRNA transcription by RNA polymerase II and snRNA transcription by RNA polymerase III. Predicted to be located in nuclear body and nucleolus. Predicted to be part of snRNA-activating protein complex. Orthologous to human SNAPC3 (small nuclear RNA activating complex polypeptide 3). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Biased expression in Thymus (RPKM 173.7), Lung (RPKM 150.4) and 9 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 5q31

Exon count:: 10

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	5	NC_086023.1 (102863867..102890573)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	5	NC_051340.1 (97817827..97868494)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	5	NC_005104.4 (101526591..101554015)

Chromosome 5 - NC_086023.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

BE105229 (e-PCR)
- UniSTS:245785

BE098610 (e-PCR)
- UniSTS:245274

RH139702 (e-PCR)
- UniSTS:221786

RH138020 (e-PCR)
- UniSTS:220107

Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables DNA binding	IEA Inferred from Electronic Annotation more info
contributes_to RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA Inferred from Biological aspect of Ancestor more info
enables RNA polymerase III type 3 promoter sequence-specific DNA binding	IBA Inferred from Biological aspect of Ancestor more info
enables bent DNA binding	IBA Inferred from Biological aspect of Ancestor more info
contributes_to core promoter sequence-specific DNA binding	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in snRNA transcription by RNA polymerase II	IBA Inferred from Biological aspect of Ancestor more info
involved_in snRNA transcription by RNA polymerase III	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
located_in nuclear body	IEA Inferred from Electronic Annotation more info
located_in nuclear body	ISO Inferred from Sequence Orthology more info
located_in nucleolus	IEA Inferred from Electronic Annotation more info
located_in nucleolus	ISO Inferred from Sequence Orthology more info
located_in nucleoplasm	ISO Inferred from Sequence Orthology more info
located_in nucleus	IEA Inferred from Electronic Annotation more info
part_of snRNA-activating protein complex	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: snRNA-activating protein complex subunit 3

Names: SNAPc subunit 3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001013212.1 → NP_001013230.1 snRNA-activating protein complex subunit 3

See identical proteins and their annotated locations for NP_001013230.1

Status: PROVISIONAL

Source sequence(s)

BC091186

UniProtKB/Swiss-Prot

Q5BK68

UniProtKB/TrEMBL

A0A8I5ZRN7, A6J848

Related

ENSRNOP00000081077.2, ENSRNOT00000103195.2

Conserved Domains (1) summary

pfam12251
Location:198 → 399

zf-SNAP50_C; snRNA-activating protein of 50kDa MW C terminal

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

NC_086023.1 Reference GRCr8

Range

102863867..102890573

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_063287942.1 → XP_063144012.1 snRNA-activating protein complex subunit 3 isoform X2
XM_039110263.2 → XP_038966191.1 snRNA-activating protein complex subunit 3 isoform X1

Conserved Domains (1) summary

pfam12251
Location:44 → 245

zf-SNAP50_C; snRNA-activating protein of 50kDa MW C terminal
XM_063287941.1 → XP_063144011.1 snRNA-activating protein complex subunit 3 isoform X1