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    Klhl32 kelch-like family member 32 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 313111, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Klhl32provided by RGD
    Official Full Name
    kelch-like family member 32provided by RGD
    Primary source
    RGD:1310364
    See related
    EnsemblRapid:ENSRNOG00000007441 AllianceGenome:RGD:1310364
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1310364
    Summary
    Orthologous to human KLHL32 (kelch like family member 32). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Brain (RPKM 42.1), Adrenal (RPKM 25.0) and 8 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Klhl32 in Genome Data Viewer
    Location:
    5q21
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 5 NC_086023.1 (43117861..43365080, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 5 NC_051340.1 (38321237..38568453, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 5 NC_005104.4 (38968479..39215203, complement)

    Chromosome 5 - NC_086023.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC134478950 Neighboring gene MMS22-like, DNA repair protein Neighboring gene aldo-keto reductase family 1 member B1-like Neighboring gene small nucleolar RNA, H/ACA box 26 Neighboring gene uncharacterized LOC134478952 Neighboring gene glutathione S-transferase P-like Neighboring gene uncharacterized LOC134478951

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    General protein information

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    Preferred Names
    kelch-like family member 32; kelch-like protein 32
    Names
    kelch-like 32

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001431161.1 → NP_001418090.1  kelch-like family member 32 isoform 1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000005
      UniProtKB/TrEMBL
      F1M9S9

    2. NM_001431162.1 → NP_001418091.1  kelch-like family member 32 isoform 2

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000005
      UniProtKB/TrEMBL
      F1M9S9

    3. NM_001431163.1 → NP_001418092.1  kelch-like family member 32 isoform 3

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000005
      UniProtKB/TrEMBL
      A0A8I6ACF1

    4. NM_001431164.1 → NP_001418093.1  kelch-like family member 32 isoform 4

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000005

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086023.1 Reference GRCr8

      Range
      43117861..43365080 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_232840.11 → XP_232840.4  kelch-like protein 32 isoform X1

      Related
      ENSRNOP00000091798.2, ENSRNOT00000100722.2
      Conserved Domains (7) summary
      smart00612
      Location:291 → 346
      Kelch; Kelch domain
      smart00875
      Location:144 → 244
      BACK; BTB And C-terminal Kelch
      PHA03098
      Location:30 → 590
      PHA03098; kelch-like protein; Provisional
      sd00038
      Location:336 → 384
      Kelch; KELCH repeat [structural motif]
      pfam00651
      Location:32 → 136
      BTB; BTB/POZ domain
      pfam01344
      Location:483 → 529
      Kelch_1; Kelch motif
      pfam13964
      Location:336 → 388
      Kelch_6; Kelch motif

    2. XM_017593707.3 → XP_017449196.1  kelch-like protein 32 isoform X4

    3. XM_017593705.2 → XP_017449194.1  kelch-like protein 32 isoform X2

      Related
      ENSRNOP00000105157.1, ENSRNOT00000148359.1

    4. XM_017593706.2 → XP_017449195.1  kelch-like protein 32 isoform X3

      Related
      ENSRNOP00000045360.6, ENSRNOT00000050653.8

    5. XM_063261279.1 → XP_063117349.1  kelch-like protein 32 isoform X5

    6. XM_039110960.2 → XP_038966888.1  kelch-like protein 32 isoform X7

      Conserved Domains (2) summary
      PHA03098
      Location:66 → 304
      PHA03098; kelch-like protein; Provisional
      sd00038
      Location:113 → 161
      Kelch; KELCH repeat [structural motif]

    7. XM_063261280.1 → XP_063117350.1  kelch-like protein 32 isoform X6

    8. XM_063261281.1 → XP_063117351.1  kelch-like protein 32 isoform X8

    Nucleotide Protein Strain
    Heading Accession and Version

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