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    Lsm8 LSM8 homolog, U6 small nuclear RNA associated [ Rattus norvegicus (Norway rat) ]

    Gene ID: 296913, updated on 9-Dec-2024

    Summary

    Official Symbol
    Lsm8provided by RGD
    Official Full Name
    LSM8 homolog, U6 small nuclear RNA associatedprovided by RGD
    Primary source
    RGD:1308442
    See related
    EnsemblRapid:ENSRNOG00000070946 AllianceGenome:RGD:1308442
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable mRNA binding activity. Predicted to be involved in mRNA splicing, via spliceosome. Predicted to be located in nucleus. Predicted to be part of Lsm2-8 complex; U2-type precatalytic spliceosome; and spliceosomal snRNP complex. Orthologous to human LSM8 (LSM8 homolog, U6 small nuclear RNA associated). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Thymus (RPKM 380.2), Spleen (RPKM 204.7) and 9 other tissues See more
    Orthologs
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    Genomic context

    See Lsm8 in Genome Data Viewer
    Location:
    4q22
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 4 NC_086022.1 (48272128..48277994)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 4 NC_051339.1 (47306259..47312125)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 4 NC_005103.4 (45555077..45560943)

    Chromosome 4 - NC_086022.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC134486735 Neighboring gene uncharacterized LOC134486736 Neighboring gene ankyrin repeat domain 7 Neighboring gene protein disulfide isomerase family A, member 6 like 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
     
    involved_in mRNA splicing, via spliceosome ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    part_of Lsm2-8 complex ISO
    Inferred from Sequence Orthology
    more info
     
    part_of U2-type precatalytic spliceosome ISO
    Inferred from Sequence Orthology
    more info
     
    part_of U4/U6 x U5 tri-snRNP complex ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    LSM8 homolog, U6 small nuclear RNA associated
    Names
    N-alpha-acetyltransferase 38, NatC auxiliary subunit

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001106585.1NP_001100055.1  LSM8 homolog, U6 small nuclear RNA associated

      See identical proteins and their annotated locations for NP_001100055.1

      Status: PROVISIONAL

      Source sequence(s)
      CH473959
      UniProtKB/TrEMBL
      A0A8I5ZNK7, A6IE42, B2RZB6
      Related
      ENSRNOP00000079477.1, ENSRNOT00000115943.2
      Conserved Domains (1) summary
      cd01727
      Location:392
      LSm8; Like-Sm protein 8

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086022.1 Reference GRCr8

      Range
      48272128..48277994
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)