Dzip1l DAZ interacting zinc finger protein 1-like [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Dzip1lprovided by RGD
Official Full Name: DAZ interacting zinc finger protein 1-likeprovided by RGD
Primary source: RGD:1311430
See related: EnsemblRapid:ENSRNOG00000014746 AllianceGenome:RGD:1311430
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: RGD1311430
Summary: Predicted to enable metal ion binding activity. Predicted to be involved in cilium assembly and regulation of protein localization. Predicted to act upstream of or within several processes, including ciliary transition zone assembly; neural tube development; and protein localization to cilium. Predicted to be located in axoneme and centriole. Predicted to be active in ciliary basal body and cytoplasm. Human ortholog(s) of this gene implicated in polycystic kidney disease 5. Orthologous to human DZIP1L (DAZ interacting zinc finger protein 1 like). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Biased expression in Heart (RPKM 47.0), Kidney (RPKM 39.6) and 8 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 8q31

Exon count:: 20

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	8	NC_086026.1 (109067466..109108390)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	8	NC_051343.1 (100188414..100229077)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	8	NC_005107.4 (107875659..107916298)

Chromosome 8 - NC_086026.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:

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Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

RH136812 (e-PCR)
- UniSTS:218901

RH139924 (e-PCR)
- UniSTS:222008

Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables metal ion binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in ciliary transition zone assembly	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within ciliary transition zone assembly	ISO Inferred from Sequence Orthology more info
involved_in cilium assembly	IBA Inferred from Biological aspect of Ancestor more info
involved_in cilium assembly	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within cilium assembly	ISO Inferred from Sequence Orthology more info
involved_in cilium assembly	ISO Inferred from Sequence Orthology more info
involved_in cilium assembly	ISS Inferred from Sequence or Structural Similarity more info
involved_in floor plate development	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within floor plate development	ISO Inferred from Sequence Orthology more info
involved_in neural tube patterning	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within neural tube patterning	ISO Inferred from Sequence Orthology more info
involved_in protein localization to cilium	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within protein localization to cilium	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within protein localization to organelle	ISO Inferred from Sequence Orthology more info
involved_in regulation of protein localization	IEA Inferred from Electronic Annotation more info
involved_in regulation of protein localization	ISO Inferred from Sequence Orthology more info
involved_in regulation of protein localization	ISS Inferred from Sequence or Structural Similarity more info
involved_in smoothened signaling pathway	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within smoothened signaling pathway	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
located_in axoneme	IEA Inferred from Electronic Annotation more info
located_in axoneme	ISO Inferred from Sequence Orthology more info
located_in cell projection	IEA Inferred from Electronic Annotation more info
located_in centriole	IEA Inferred from Electronic Annotation more info
located_in centriole	ISO Inferred from Sequence Orthology more info
located_in centriole	ISS Inferred from Sequence or Structural Similarity more info
is_active_in ciliary basal body	IBA Inferred from Biological aspect of Ancestor more info
located_in ciliary basal body	IEA Inferred from Electronic Annotation more info
located_in ciliary basal body	ISO Inferred from Sequence Orthology more info
located_in ciliary basal body	ISS Inferred from Sequence or Structural Similarity more info
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
located_in cytoplasm	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: cilium assembly protein DZIP1L

Names: DAZ interacting protein 1-like; DAZ-interacting protein 1-like protein; zinc finger protein DZIP1L

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.