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    Pwwp4 PWWP domain containing 4 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 690082, updated on 27-Nov-2024

    Summary

    Official Symbol
    Pwwp4provided by RGD
    Official Full Name
    PWWP domain containing 4provided by RGD
    Primary source
    RGD:1585131
    See related
    EnsemblRapid:ENSRNOG00000068777 AllianceGenome:RGD:1585131
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Expression
    Biased expression in Testes (RPKM 14.5), Adrenal (RPKM 2.8) and 3 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Pwwp4 in Genome Data Viewer
    Location:
    Xq37
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) X NC_086039.1 (156159344..156165457)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) X NC_051356.1 (151008141..151014223)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (146966354..146974136, complement)

    Chromosome X - NC_086039.1Genomic Context describing neighboring genes Neighboring gene X-linked lymphocyte-regulated 3A Neighboring gene X-linked lymphocyte-regulated 5C Neighboring gene dnaJ homolog subfamily C member 8-like Neighboring gene zinc finger protein 275 Neighboring gene U2 spliceosomal RNA

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General protein information

    Preferred Names
    PWWP domain-containing DNA repair factor 4
    Names
    PWWP domain-containing DNA repair factor 3B-like
    PWWP domain-containing protein MUM1-like
    PWWP domain-containing protein MUM1L1-like

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001408900.1NP_001395829.1  PWWP domain-containing DNA repair factor 4

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000021
      UniProtKB/TrEMBL
      A0A8I5ZV76
      Related
      ENSRNOP00000083316.1, ENSRNOT00000109322.2

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086039.1 Reference GRCr8

      Range
      156159344..156165457
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017590172.3XP_017445661.2  PWWP domain-containing DNA repair factor 4 isoform X1

      UniProtKB/TrEMBL
      A0A8I5ZV76
      Conserved Domains (2) summary
      cd06080
      Location:407486
      MUM1_like; Mutated melanoma-associated antigen 1 (MUM-1) is a melanoma-associated antigen (MAA). MUM-1 belongs to the mutated or aberrantly expressed type of MAAs, along with antigens such as CDK4, beta-catenin, gp100-in4, p15, and N-acetylglucosaminyltransferase ...
      PHA03377
      Location:113242
      PHA03377; EBNA-3C; Provisional