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    Mycbp Myc binding protein [ Rattus norvegicus (Norway rat) ]

    Gene ID: 100361133, updated on 9-Dec-2024

    Summary

    Official Symbol
    Mycbpprovided by RGD
    Official Full Name
    Myc binding proteinprovided by RGD
    Primary source
    RGD:2320727
    See related
    EnsemblRapid:ENSRNOG00000065724 AllianceGenome:RGD:2320727
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable transcription coactivator activity. Predicted to be involved in regulation of DNA-templated transcription and spermatogenesis. Predicted to be located in mitochondrion and nucleoplasm. Predicted to be active in nucleus. Orthologous to human MYCBP (MYC binding protein). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Kidney (RPKM 178.2), Testes (RPKM 161.8) and 9 other tissues See more
    Orthologs
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    Genomic context

    See Mycbp in Genome Data Viewer
    Location:
    5q36
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 5 NC_086023.1 (141420727..141427938)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 5 NC_051340.1 (136135955..136143163)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 5 NC_005104.4 (141560192..141567399)

    Chromosome 5 - NC_086023.1Genomic Context describing neighboring genes Neighboring gene rhomboid like 2 Neighboring gene uncharacterized LOC134479029 Neighboring gene uncharacterized LOC134479028 Neighboring gene Ras-related GTP binding C Neighboring gene uncharacterized LOC120102974

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables transcription coactivator activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables transcription coactivator activity ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    involved_in positive regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in regulation of DNA-templated transcription IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in regulation of DNA-templated transcription ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in spermatogenesis ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
     
    located_in mitochondrion ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    C-Myc-binding protein
    Names
    c-myc binding protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001271324.2NP_001258253.1  C-Myc-binding protein

      See identical proteins and their annotated locations for NP_001258253.1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000005
      UniProtKB/TrEMBL
      A0A8I5ZT87, A6IS38, D4A7F2
      Related
      ENSRNOP00000081590.1, ENSRNOT00000100258.2
      Conserved Domains (1) summary
      cd21937
      Location:4294
      ZIP_MycBP-like; leucine zipper domain found in c-Myc-binding protein and similar proteins

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086023.1 Reference GRCr8

      Range
      141420727..141427938
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)