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    Paxbp1 PAX3 and PAX7 binding protein 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 681004, updated on 9-Dec-2024

    Summary

    Official Symbol
    Paxbp1provided by RGD
    Official Full Name
    PAX3 and PAX7 binding protein 1provided by RGD
    Primary source
    RGD:1584739
    See related
    EnsemblRapid:ENSRNOG00000002036 AllianceGenome:RGD:1584739
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Gcfc1
    Summary
    Predicted to enable histone methyltransferase binding activity. Predicted to be involved in positive regulation of transcription by RNA polymerase II. Predicted to act upstream of or within positive regulation of myoblast proliferation and regulation of skeletal muscle satellite cell proliferation. Predicted to be active in nucleus. Orthologous to human PAXBP1 (PAX3 and PAX7 binding protein 1). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Thymus (RPKM 147.3), Adrenal (RPKM 130.6) and 9 other tissues See more
    Orthologs
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    Genomic context

    See Paxbp1 in Genome Data Viewer
    Location:
    11q11
    Exon count:
    18
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 11 NC_086029.1 (43758116..43787624, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 11 NC_051346.1 (30272037..30301504, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 11 NC_005110.4 (31184456..31213891, complement)

    Chromosome 11 - NC_086029.1Genomic Context describing neighboring genes Neighboring gene cilia and flagella associated protein 298 Neighboring gene synaptojanin 1 Neighboring gene exosomal polycystin 1 interacting protein Neighboring gene uncharacterized LOC102554018

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables DNA binding  
    enables histone methyltransferase binding  
    Component Evidence Code Pubs
    is_active_in nucleus  
    located_in nucleus  

    General protein information

    Preferred Names
    PAX3- and PAX7-binding protein 1
    Names
    GC-rich sequence DNA-binding factor 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001426992.1NP_001413921.1  PAX3- and PAX7-binding protein 1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000011
      UniProtKB/TrEMBL
      D4A8C8
      Related
      ENSRNOP00000002800.5, ENSRNOT00000002800.8

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086029.1 Reference GRCr8

      Range
      43758116..43787624 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    RNA

    1. XR_005491197.2 RNA Sequence

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