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    Rassf4 Ras association domain family member 4 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 362423, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Rassf4provided by RGD
    Official Full Name
    Ras association domain family member 4provided by RGD
    Primary source
    RGD:1307785
    See related
    EnsemblRapid:ENSRNOG00000013526 AllianceGenome:RGD:1307785
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to be involved in signal transduction. Orthologous to human RASSF4 (Ras association domain family member 4). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Spleen (RPKM 76.5), Lung (RPKM 51.7) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Rassf4 in Genome Data Viewer
    Location:
    4q42
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 4 NC_086022.1 (151569984..151605203, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 4 NC_051339.1 (149897525..149932658, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 4 NC_005103.4 (148769092..148804295, complement)

    Chromosome 4 - NC_086022.1Genomic Context describing neighboring genes Neighboring gene transfer RNA cysteine (anticodon GCA) 29 Neighboring gene zinc finger protein 422 Neighboring gene DEPP autophagy regulator 1 Neighboring gene transmembrane protein 72 Neighboring gene small nucleolar RNA SNORA17

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334, Free PMC Article
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC105606

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in signal transduction IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    ras association domain-containing protein 4
    Names
    Ras association (RalGDS/AF-6) domain family 4
    Ras association (RalGDS/AF-6) domain family member 4

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001024275.2 → NP_001019446.1  ras association domain-containing protein 4

      See identical proteins and their annotated locations for NP_001019446.1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000004
      UniProtKB/Swiss-Prot
      Q566C5
      UniProtKB/TrEMBL
      A6IL26
      Related
      ENSRNOP00000018101.5, ENSRNOT00000018101.9
      Conserved Domains (1) summary
      cl00155
      Location:176 → 262
      UBQ; Ubiquitin-like proteins

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086022.1 Reference GRCr8

      Range
      151569984..151605203 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017592701.3 → XP_017448190.1  ras association domain-containing protein 4 isoform X1

      UniProtKB/Swiss-Prot
      Q566C5
      UniProtKB/TrEMBL
      A6IL26
      Conserved Domains (1) summary
      cl00155
      Location:176 → 262
      UBQ; Ubiquitin-like proteins

    2. XM_039107862.2 → XP_038963790.1  ras association domain-containing protein 4 isoform X2

      UniProtKB/TrEMBL
      A0A8I5YBY7
      Related
      ENSRNOP00000077644.1, ENSRNOT00000101033.2
      Conserved Domains (1) summary
      cd17222
      Location:176 → 262
      RA_RASSF4; Ras-associating (RA) domain found in Ras-association domain-containing protein 4 (RASSF4)

    3. XM_039107863.2 → XP_038963791.1  ras association domain-containing protein 4 isoform X3

      Conserved Domains (1) summary
      cd17222
      Location:106 → 192
      RA_RASSF4; Ras-associating (RA) domain found in Ras-association domain-containing protein 4 (RASSF4)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q566C5.1 GenPept UniProtKB/Swiss-Prot:Q566C5

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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