Rpl3l ribosomal protein L3-like [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Rpl3lprovided by RGD
Official Full Name: ribosomal protein L3-likeprovided by RGD
Primary source: RGD:1306315
See related: EnsemblRapid:ENSRNOG00000014641 AllianceGenome:RGD:1306315
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary: Predicted to enable RNA binding activity. Predicted to be a structural constituent of ribosome. Predicted to be involved in negative regulation of myotube differentiation; regulation of striated muscle tissue development; and translation. Predicted to be part of cytosolic large ribosomal subunit. Human ortholog(s) of this gene implicated in dilated cardiomyopathy 2D. Orthologous to human RPL3L (ribosomal protein L3 like). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Biased expression in Muscle (RPKM 655.9) and Heart (RPKM 287.5) See more
Orthologs: human mouse all
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Genomic context

Location:: 10q12

Exon count:: 10

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	10	NC_086028.1 (14258446..14268989)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	10	NC_051345.1 (13753914..13764458)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	10	NC_005109.4 (14094769..14105312)

Chromosome 10 - NC_086028.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables RNA binding	IBA Inferred from Biological aspect of Ancestor more info
enables structural constituent of ribosome	IBA Inferred from Biological aspect of Ancestor more info
enables structural constituent of ribosome	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
involved_in negative regulation of myotube differentiation	ISO Inferred from Sequence Orthology more info
involved_in regulation of striated muscle tissue development	ISO Inferred from Sequence Orthology more info
involved_in translation	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
part_of cytosolic large ribosomal subunit	IBA Inferred from Biological aspect of Ancestor more info
part_of cytosolic large ribosomal subunit	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: ribosomal protein uL3-like

Names: 60S ribosomal protein L3-like

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001191589.1 → NP_001178518.1 ribosomal protein uL3-like

Status: PROVISIONAL

Source sequence(s)

JAXUCZ010000010

UniProtKB/TrEMBL

D4A9G1

Related

ENSRNOP00000019660.5, ENSRNOT00000019660.9

Conserved Domains (2) summary

PTZ00103
Location:1 → 400

PTZ00103; 60S ribosomal protein L3; Provisional

cl00324
Location:7 → 373

RplC; Ribosomal protein L3 [Translation, ribosomal structure and biogenesis]