Dnajc17 DnaJ heat shock protein family (Hsp40) member C17 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Dnajc17provided by RGD
Official Full Name: DnaJ heat shock protein family (Hsp40) member C17provided by RGD
Primary source: RGD:1308015
See related: EnsemblRapid:ENSRNOG00000012368 AllianceGenome:RGD:1308015
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: RGD1308015
Summary: Predicted to enable RNA binding activity. Predicted to be involved in spliceosomal complex disassembly. Predicted to act upstream of or within negative regulation of transcription by RNA polymerase II. Located in cytoplasm and nucleus. Orthologous to human DNAJC17 (DnaJ heat shock protein family (Hsp40) member C17). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Biased expression in Thymus (RPKM 70.3), Spleen (RPKM 54.2) and 9 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 3q35

Exon count:: 12

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	3	NC_086021.1 (126616043..126649599, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	3	NC_051338.1 (106162197..106195771, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	3	NC_005102.4 (110980074..111013602, complement)

Chromosome 3 - NC_086021.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

C87112 (e-PCR)
- UniSTS:208393

RH130531 (e-PCR)
- UniSTS:213815

AI029839 (e-PCR)
- UniSTS:246073

RH139445 (e-PCR)
- UniSTS:221531

D9Bwg1371e (e-PCR), detects polymorphism
- UniSTS:142741

RH128082 (e-PCR)
- UniSTS:211390

AU047742 (e-PCR)
- UniSTS:115910

RH143671 (e-PCR)
- UniSTS:232917

Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables RNA binding	IEA Inferred from Electronic Annotation more info
enables nucleic acid binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in negative regulation of transcription by RNA polymerase II	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within negative regulation of transcription by RNA polymerase II	ISO Inferred from Sequence Orthology more info
involved_in spliceosomal complex disassembly	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
located_in cytoplasm	IDA Inferred from Direct Assay more info	PubMed
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
located_in nucleus	IDA Inferred from Direct Assay more info	PubMed
located_in nucleus	IEA Inferred from Electronic Annotation more info
part_of spliceosomal complex	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: dnaJ homolog subfamily C member 17

Names: DnaJ (Hsp40) homolog, subfamily C, member 17

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001191740.1 → NP_001178669.1 dnaJ homolog subfamily C member 17

Status: PROVISIONAL

Source sequence(s)

JAXUCZ010000003

UniProtKB/Swiss-Prot

D3ZSC8

UniProtKB/TrEMBL

A6HPE4

Related

ENSRNOP00000090029.2, ENSRNOT00000119119.2

Conserved Domains (2) summary

cd12429
Location:184 → 247

RRM_DNAJC17; RNA recognition motif in the DnaJ homolog subfamily C member 17

pfam00226
Location:11 → 73

DnaJ; DnaJ domain