Pianp PILR alpha associated neural protein [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Pianpprovided by RGD
Official Full Name: PILR alpha associated neural proteinprovided by RGD
Primary source: RGD:1304952
See related: EnsemblRapid:ENSRNOG00000017052 AllianceGenome:RGD:1304952
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: PANP; leda-1; RGD1304952
Summary: Predicted to enable protein domain specific binding activity. Predicted to be involved in regulation of immune response. Predicted to act upstream of or within several processes, including brain development; glutamate secretion; and visual learning. Located in basolateral plasma membrane. Orthologous to human PIANP (PILR alpha associated neural protein). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Biased expression in Brain (RPKM 10.9), Adrenal (RPKM 10.6) and 9 other tissues See more
Orthologs: human mouse all
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

Location:: 4q42

Exon count:: 9

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	4	NC_086022.1 (159482678..159491085)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	4	NC_051339.1 (157796425..157804842)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	4	NC_005103.4 (157508862..157517676)

Chromosome 4 - NC_086022.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help

See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

Go to the top of the page Help

Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables protein domain specific binding	IEA Inferred from Electronic Annotation more info
enables protein domain specific binding	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
involved_in cerebellum development	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within cerebellum development	ISO Inferred from Sequence Orthology more info
involved_in dentate gyrus development	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within dentate gyrus development	ISO Inferred from Sequence Orthology more info
involved_in gamma-aminobutyric acid signaling pathway	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within gamma-aminobutyric acid signaling pathway	ISO Inferred from Sequence Orthology more info
involved_in gene expression	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within gene expression	ISO Inferred from Sequence Orthology more info
involved_in glutamate secretion	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within glutamate secretion	ISO Inferred from Sequence Orthology more info
involved_in homeostasis of number of cells	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within homeostasis of number of cells	ISO Inferred from Sequence Orthology more info
involved_in regulation of immune response	IEA Inferred from Electronic Annotation more info
involved_in response to stress	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within response to stress	ISO Inferred from Sequence Orthology more info
involved_in social behavior	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within social behavior	ISO Inferred from Sequence Orthology more info
involved_in visual learning	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within visual learning	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
located_in basolateral plasma membrane	IDA Inferred from Direct Assay more info	PubMed
is_active_in membrane	IBA Inferred from Biological aspect of Ancestor more info
located_in membrane	IEA Inferred from Electronic Annotation more info
located_in presynapse	IEA Inferred from Electronic Annotation more info
is_active_in presynapse	ISO Inferred from Sequence Orthology more info

General protein information

Go to the top of the page Help

Preferred Names: PILR alpha-associated neural protein

Names: PILR-associating neural protein; liver endothelial differentiation-associated protein-1; paired immunoglobin-like type 2 receptor-associating neural protein; uncharacterized protein C12orf53 homolog

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001014059.1 → NP_001014081.1 PILR alpha-associated neural protein precursor

See identical proteins and their annotated locations for NP_001014081.1

Status: PROVISIONAL

Source sequence(s)

BC085924

UniProtKB/Swiss-Prot

Q5U2P6

UniProtKB/TrEMBL

A6ILP0

Related

ENSRNOP00000060404.2, ENSRNOT00000065846.4

Conserved Domains (1) summary

pfam15298
Location:191 → 232

AJAP1_PANP_C; AJAP1/PANP C-terminus

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

NC_086022.1 Reference GRCr8

Range

159482678..159491085

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_039107681.2 → XP_038963609.1 PILR alpha-associated neural protein isoform X2

UniProtKB/TrEMBL

A0A8I6AV41, A6ILN7
XM_039107680.2 → XP_038963608.1 PILR alpha-associated neural protein isoform X2

UniProtKB/TrEMBL

A0A8I6AV41, A6ILN7
XM_008763286.4 → XP_008761508.1 PILR alpha-associated neural protein isoform X2

See identical proteins and their annotated locations for XP_008761508.1

UniProtKB/TrEMBL

A0A8I6AV41, A6ILN7

Related

ENSRNOP00000097907.1, ENSRNOT00000099374.2

Conserved Domains (1) summary

pfam15298
Location:191 → 232

AJAP1_PANP_C; AJAP1/PANP C-terminus
XM_017592652.3 → XP_017448141.1 PILR alpha-associated neural protein isoform X2

UniProtKB/TrEMBL

A0A8I6AV41, A6ILN7

Conserved Domains (1) summary

pfam15298
Location:191 → 232

AJAP1_PANP_C; AJAP1/PANP C-terminus
XM_008763285.4 → XP_008761507.1 PILR alpha-associated neural protein isoform X1

Conserved Domains (1) summary

pfam15298
Location:240 → 281

AJAP1_PANP_C; AJAP1/PANP C-terminus
XM_006237370.5 → XP_006237432.1 PILR alpha-associated neural protein isoform X2

See identical proteins and their annotated locations for XP_006237432.1

UniProtKB/TrEMBL

A0A8I6AV41, A6ILN7

Conserved Domains (1) summary

pfam15298
Location:191 → 232

AJAP1_PANP_C; AJAP1/PANP C-terminus